特定分子特征揭示CMML对地西他滨的应答 [RNA-seq]

资源简介

特定分子特征揭示CMML对地西他滨的应答 [RNA-seq]

【数据集背景】

本数据集源站标题为《Specific molecular signatures underlie response to decitabine in CMML [RNA-seq]》。源站首次发布：Sep 05 201。

【数据内容】

源站原始描述：Myelodysplastic syndromes and chronic myelomonocytic leukemia (CMML) are characterized by mutations in epigenetic modifiers and aberrant DNA methylation. DNA methyltransferase inhibitors (DMTis) are used to treat these disorders, but response is highly variable with few means to predict which patients will benefit. To develop a molecular means of predicting response at diagnosis, we examined baseline differences in mutations, DNA methylation, and gene expression in 40 CMML patients responsive an…

【数据结构与技术规格】

文件数 1 个。

【主题与分类】

主题标签：GPL11154、9606。

【获取与许可】

源站页面：https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE61162

【使用注意】

· 源站最后修改于 May 15 201，引用时请注意版本时效。