人类BBS4基因异位表达可拯救Bbs4基因敲除小鼠的Bardet-Biedl综合征表型

资源简介

人类BBS4基因异位表达可拯救Bbs4基因敲除小鼠的Bardet-Biedl综合征表型

【数据集背景】

本数据集源站标题为《Ectopic Expression of Human BBS4 Can Rescue Bardet-Biedl Syndrome Phenotypes in Bbs4 Null Mice》。配套论文《Ectopic Expression of Human BBS4 Can Rescue Bardet-Biedl Syndrome Phenotypes in Bbs4 Null Mice》发表于 PLoS ONE（2013），DOI：10.1371/journal.pone.0059101。源站首次发布：2013-03-16。

【数据内容】

源站原始描述：Bardet-Biedl syndrome (BBS) is a genetically heterogeneous autosomal recessive disorder characterized by obesity, retinal degeneration, polydactyly, hypogenitalism and renal defects. Recent findings have associated the etiology of the disease with cilia, and BBS proteins have been implicated in trafficking various ciliary cargo proteins. To date, 17 different genes have been reported for BBS among which BBS1 is the most common cause of the disease followed by BBS10, and BBS4. A murine model of B…

【数据结构与技术规格】

文件数 3 个，合计 5.33 MB。Figure_S1.tif：image/tiff，1.67 MB。Figure_S2.tif：image/tiff，1.64 MB。Figure_S3.tif：image/tiff，2.02 MB。数据集 DOI：10.1371/journal.pone.0059101。

【主题与分类】

源站学科分类：Genetics。主题标签：ectopic、bardet-biedl、phenotypes、null、mice。

【适用方向】

源站学科分类标注为 Genetics。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Ectopic_Expression_of_Human_BBS4_Can_Rescue_Bardet_Biedl_Syndrome_Phenotypes_in_Bbs4_Null_Mice__/653503

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Chamling, Xitiz; Seo, Seongjin; Bugge, Kevin; Searby, Charles; F. Guo, Deng; V. Drack, Arlene; et al. (2016). Ectopic Expression of Human BBS4 Can Rescue Bardet-Biedl Syndrome Phenotypes in Bbs4 Null Mice. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-02，引用时请注意版本时效。