28例疑似林奇综合征患者肿瘤免疫组化染色与胚系突变相关性数据集

资源简介

28例疑似林奇综合征患者肿瘤免疫组化染色与胚系突变相关性数据集

【数据集背景】

本数据集源站标题为《Correlation between tumor immunohistochemical (IHC) stains and germline mutations in 28 suspected Lynch Syndrome patients.》。配套论文《Systematic Study on Genetic and Epimutational Profile of a Cohort of Amsterdam Criteria-Defined Lynch Syndrome in Singapore》发表于 PLoS ONE（2014），DOI：10.1371/journal.pone.0094170。源站首次发布：2014-04-07。

【数据内容】

源站原始描述：$, Tumor IHC sensitivity for germline defects. †, LOVD, London open variation database (V2.0 build 35) maintained by International Society of Gastroenterological Hereditary Tumors (InSiGHT). Variants were classified according to Consensus InSiGHT Classification v.1.9: 5/09/2013. ‡, HGMD, human gene mutation database. Dis causing, disease causative mutation; Our data were checked against this database as of 10 Jan 2014. Novel mutations were highlighted in bold; VUS, variant of uncertain significa…

【数据结构与技术规格】

文件数 1 个，合计 13.82 KB。Table_2.xls：application/vnd.ms-excel，13.82 KB。数据集 DOI：10.1371/journal.pone.0094170.t002。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：Computational biology、Evolutionary biology、population genetics、genetics、mutation、Population biology、Clinical genetics、Diagnostic medicine、epidemiology、Genetic epidemiology。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Correlation_between_tumor_immunohistochemical_IHC_stains_and_germline_mutations_in_28_suspected_Lynch_Syndrome_patients_/989354

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Liu, Yanqun; Hoe Chew, Min; Wei Goh, Xue; Yong Tan, Soo; Tien Tau Loi, Carol; Ming Tan, Yuen; et al. (2015). Correlation between tumor immunohistochemical (IHC) stains and germline mutations in 28 suspected Lynch Syndrome patients.. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。