CPN2通过抑制NF-κB通路和调节免疫反应缓解隐睾症

资源简介

CPN2通过抑制NF-κB通路和调节免疫反应缓解隐睾症

【数据集背景】

本数据集源站标题为《CPN2 alleviates cryptorchidism by inhibiting the NF-κB pathway and regulating immune responses》。配套论文《CPN2 alleviates cryptorchidism by inhibiting the NF-κB pathway and regulating immune responses》发表于 Autoimmunity（2025），DOI：10.1080/08916934.2025.2538860。项目资助方：This study was supported by Suzhou (Research on the Application of Key Technologies for Livelihood Science and Technology) Project (SS201754).。源站首次发布：2025-07-28。

【数据内容】

源站原始描述：Cryptorchidism, a common male reproductive disorder characterized by undescended testes, is associated with infertility and increased cancer risk. While its etiology remains incompletely understood, accumulating evidence suggests that immune-inflammatory responses contribute to disease progression. This study investigated the role of carboxypeptidase N subunit 2 (CPN2) in modulating immune activation and testicular pathology via the NF-κB signaling pathway. Key regulatory genes were identified t…

【数据结构与技术规格】

文件数 5 个，合计 8.90 MB。iaut_a_2538860_sm5655.jpg：image/jpeg，1.01 MB。iaut_a_2538860_sm5654.jpg：image/jpeg，1.06 MB。iaut_a_2538860_sm5653.jpg：image/jpeg，2.85 MB。数据集 DOI：10.6084/m9.figshare.29657152.v1。

【主题与分类】

源站学科分类：Biochemistry、Medicine、Microbiology、Cell Biology、Physiology、Chemical Sciences not elsewhere classified。主题标签：Cryptorchidism、CPN2、NF-κB、Single-Cell sequencing、transcriptomics。

【适用方向】

源站学科分类标注为 Biochemistry、Medicine、Microbiology、Cell Biology、Physiology、Chemical Sciences not elsewhere classified。

【获取与许可】

源站页面：https://tandf.figshare.com/articles/dataset/CPN2_alleviates_cryptorchidism_by_inhibiting_the_NF-_B_pathway_and_regulating_immune_responses/29657152

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：CPN2 alleviates cryptorchidism by inhibiting the NF-κB pathway and regulating immune responses. Taylor & Francis. Wang, Lei; Lu, Lu; Guo, Xia; Shao, Feng; Ma, Hai-Jun; Zhou, Yun

【使用注意】

· 源站最后修改于 2025-12-18，引用时请注意版本时效。