雾化声波气溶胶递送妥布霉素治疗囊性纤维化患者慢性鼻窦炎
该数据集来自 clinicaltrials.gov,主题为雾化声波气溶胶递送妥布霉素用于治疗囊性纤维化患者的慢性鼻窦炎,属于呼吸系统疾病范畴

基本信息
资源简介
雾化声波气溶胶递送妥布霉素治疗囊性纤维化患者慢性鼻窦炎
该数据集来自 clinicaltrials.gov,主题为雾化声波气溶胶递送妥布霉素用于治疗囊性纤维化患者的慢性鼻窦炎,属于呼吸系统疾病范畴。数据覆盖囊性纤维化、鼻窦炎与肺部疾病等条件,涉及 CFTR 蛋白缺陷导致黏液黏稠、纤毛功能下降、细菌定植与感染等机制背景。可用于了解该治疗方向的临床研究信息,支持呼吸系统疾病相关研究中的检索、分类与知识整理(来源 clinicaltrials.gov)。
【数据内容】
源站描述(机器翻译,仅供参考):条件:囊性纤维化、鼻窦炎、肺部疾病。囊性纤维化(CF)是白种人群中最常见的致死性常染色体隐性遗传病,约每 3000 名儿童中影响 1 名,携带者频率为 1:25。它是一种多系统疾病,其中肺部和鼻窦受累发生于 90-100% 的患者,且高达 86% 的儿童有鼻息肉。CF 患者由于囊性纤维化跨膜传导调节因子(CFTR)蛋白缺陷而发展为慢性鼻窦炎(CRS)。衬覆鼻旁窦和鼻的膜与衬覆肺的膜相同。与下气道(LAW)一样,CFTR 蛋白缺陷导致黏液黏稠。因此黏液纤毛功能降低,这促进细菌定植并最终导致感染,从而引起鼻窦炎。在过去几十年中,下气道感染是最突出的
【主题与分类】
主题标签:Cystic Fibrosis、Rhinosinusitis、Lung Diseases。本站分类:呼吸系统疾病。
【获取与许可】
源站页面:https://clinicaltrials.gov/study/NCT02888730
下载信息
注册下载
需要注册 Kaggle 账号并登录后下载,适合需要跟踪下载记录和使用 API 的用户。
暂未开放公开下载
无需注册即可直接获取公开样本或文档,适合快速预览和评估数据集质量。
免登录当前数据集主要来源为 Kaggle 公开托管,完整影像包建议通过原始链接或 Kaggle API 获取。
使用方式
数据集获取
源站:https://clinicaltrials.gov/study/NCT02888730
标准获取流程:
- 访问源站链接,注册/登录账号;
- 进入数据集详情页,按页面指引申请权限或直接下载;
- 部分平台提供 SDK,例如:
- OpenDataLab:
pip install openxlab后openxlab.dataset.get(...) - ModelScope:
pip install modelscope后modelscope download - 天池: 登录后页面提供直链下载
以源站「数据下载/使用文档」页面为准。
- OpenDataLab:
数据说明
Conditions: Cystic Fibrosis, Rhinosinusitis, Lung Diseases. Cystic fibrosis (CF) is the most common lethal autosomal recessive disorder in the Caucasian population affecting ~1:3000 children, with a carrier frequency of 1:25. It is a multisystem disorder where pulmonary and sinonasal involvements occur in 90-100% of patients, and up to 86% of children have nasal polyps . Patients with CF develop chronic rhinosinusitis (CRS) due to the defect in the cystic fibrosis Transmembrane Regulator (CFTR) protein. The membrane lining the paranasal sinuses and the nose is identical to the membrane lining the lungs. As in lower airways (LAW) the defect CFTR protein result in viscous mucus . Consequently mucociliary function is reduced, which facilitates bacterial colonization and eventually infection leading to rhinosinusitis . In the past decades infection of the lower airways was the most prominent focus in treatment protocols for CF. Over the years infection of the upper airways (UAW) gradually gained more attention in CF. Previous research in the microbiology of the upper airways (UAW) in CF displayed that Haemophilus influenzae, Pseudomonas aeruginosa and Staphylococcus aureus were most frequently cultures from the UAW . Since several studies showed concordance between organisms in the UAW and the LAW in CF, the hypothesis evolved that the UAW might influence the patient pulmonary status . Moreover, comparison of UAW and and LAW cultures in CF adult patients showed that Pseudomonas aeruginosa can be cultured from the UAW after eradication therapy which may suggest persistence of Pseudomonas aeruginosa in the UAW . This problem is highlighted in double lung transplant where UAW also appears as a protective niche of adapted clones of bacteria, which can intermittently spread this pathogen to the lung. CRS treatment in CF patients is based on daily nasal lavages but above all on local or systemic antibiotic treatments to eradicate bacteria in sinuses . Local therapy is favoured in CRS treatment of CF patients to avoid antibiotic side e
数据加载示例(图像类)
from PIL import Image
import glob, os
files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
+ glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
+ glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)
# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path) # 要求 子目录=类别
目录组织与标注格式以源站说明和下载后实际文件为准。
需要用于商业化训练或医疗器械注册(NMPA/FDA)?
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