CFTR-/- 绵羊早期胆囊和肝脏疾病数据集

资源简介

CFTR-/- 绵羊早期胆囊和肝脏疾病数据集

【数据集背景】

本数据集源站标题为《Early gall bladder and liver disease in the CFTR-/- sheep》。项目资助方：Cystic Fibrosis Foundation (POLEJA18G0, LEIR21G0, HARRIS21G0, HARRIS23P0, POLEJA23P0), and by the US Department of Agriculture Multistate Project W-4171 (IAP) and the Utah Agricultural Experiment Station (Project 1343).。源站首次发布：2025-10-09。

【数据内容】

源站原始描述：The initiating cellular events in cystic fibrosis (CF) hepatobiliary disease are not well characterized, in part due to lack of accessibility of primary tissues. However, enhanced longevity due to highly effective modulator therapies has generated renewed interest in key aspects of liver and gallbladder disease, and how these might be treated in people with CF (pwCF). To extend the CF hepatobiliary knowledgebase, we performed a transcriptomic analysis of liver and gallbladder development in the…

【数据结构与技术规格】

文件数 6 个，合计 4.61 MB。Meckler_Combined Supplementary Figures.pdf：application/pdf，2.22 MB。Meckler_Table S1 Gall Bladder 987_DEG_FDR-0.01_FC-1.5.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，35.76 KB。Meckler_Table S2 Gall Bladder 987_DEG_FDR-0.05_FC-1.5.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，1.02 MB。数据集 DOI：10.6084/m9.figshare.30316051.v1。

【主题与分类】

源站学科分类：Other biomedical and clinical sciences not elsewhere classified。主题标签：Cystic Fibrosis、Liver、Gallbladder、Development、Transcriptomics、Gene Regulation、In utero。

【适用方向】

源站学科分类标注为 Other biomedical and clinical sciences not elsewhere classified。

【获取与许可】

源站页面：https://figshare.com/articles/dataset/Early_gall_bladder_and_liver_disease_in_the_i_CFTR_i_sup_em_-_-_em_sup_sheep/30316051

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Harris, Ann; Meckler, Frederick; Van Wettere, Arnaud; Umrigar, Ayushi; BEBEK, GURKAN; Viotti Perisse, Iuri; et al. (2025). Early gall bladder and liver disease in the CFTR-/- sheep. figshare. Dataset

【使用注意】

· 源站最后修改于 2025-10-16，引用时请注意版本时效。