自体引流与机械叩击在囊性纤维化患儿中的比较

本数据集来自 clinicaltrials.gov,主题为囊性纤维化(CF)患儿中自体引流与机械叩击的比较。CF 是由 CFTR 基因突变引起的常染色体隐性遗传病,可导致氯离子和水跨上皮转运受损,在呼吸系统等部位形成黏稠分泌物,引起慢性气道阻塞、反复肺部感染、持续炎症、进行性肺损伤及呼吸功能下降

Riphah International UniversityRiphah International University
clinicaltrials
浏览 3
基因组回归Cystic Fibrosis (CF)
Autogenic Drainage Versus Mechanical Percussion in Children With Cystic Fibrosis

基本信息

模态
基因组
任务类型
回归
创建/更新时间
2026-10-12

资源简介

自体引流与机械叩击在囊性纤维化患儿中的比较

本数据集来自 clinicaltrials.gov,主题为囊性纤维化(CF)患儿中自体引流与机械叩击的比较。CF 是由 CFTR 基因突变引起的常染色体隐性遗传病,可导致氯离子和水跨上皮转运受损,在呼吸系统等部位形成黏稠分泌物,引起慢性气道阻塞、反复肺部感染、持续炎症、进行性肺损伤及呼吸功能下降。尽管药物治疗与支持性护理不断进步,肺部并发症仍是 CF 患者致病和致死的主要原因,气道廓清治疗是呼吸管理的基本组成部分。该数据可用于比较两种气道廓清方式在儿科 CF 人群中的效果(来源 clinicaltrials.gov)。

【数据内容】

源站描述(机器翻译,仅供参考):疾病:囊性纤维化(CF)。囊性纤维化(CF)是一种由囊性纤维化跨膜传导调节因子(CFTR)基因突变引起的、限制寿命的常染色体隐性遗传病。CFTR 蛋白功能障碍导致氯离子和水跨上皮表面转运受损,从而在多个器官系统、尤其是呼吸道中产生黏稠、脱水的分泌物。气道内黏稠黏液积聚可导致慢性气道阻塞、反复肺部感染、持续炎症、进行性肺损伤以及呼吸功能下降。尽管药物治疗和支持性护理取得进展,肺部并发症仍是囊性纤维化患者致病和致死的主要原因。气道廓清治疗是呼吸管理的基本组成部分

【主题与分类】

主题标签:Cystic Fibrosis (CF)。本站分类:呼吸系统疾病。

【获取与许可】

源站页面:https://clinicaltrials.gov/study/NCT07729787

官方服务

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下载信息

注册下载

需要注册 Kaggle 账号并登录后下载,适合需要跟踪下载记录和使用 API 的用户。

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当前数据集主要来源为 Kaggle 公开托管,完整影像包建议通过原始链接或 Kaggle API 获取。

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使用方式

数据集获取

源站:https://clinicaltrials.gov/study/NCT07729787

标准获取流程:

  1. 访问源站链接,注册/登录账号;
  2. 进入数据集详情页,按页面指引申请权限或直接下载;
  3. 部分平台提供 SDK,例如:
    • OpenDataLab: pip install openxlab 后 openxlab.dataset.get(...)
    • ModelScope: pip install modelscope 后 modelscope download
    • 天池: 登录后页面提供直链下载
      以源站「数据下载/使用文档」页面为准。

数据说明

Conditions: Cystic Fibrosis (CF). Cystic fibrosis (CF) is a life-limiting autosomal recessive genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Dysfunction of the CFTR protein leads to impaired chloride and water transport across epithelial surfaces, resulting in the production of thick, dehydrated secretions in multiple organ systems, particularly the respiratory tract. The accumulation of viscous mucus within the airways contributes to chronic airway obstruction, recurrent pulmonary infections, persistent inflammation, progressive lung damage, and declining respiratory function. Despite advances in pharmacological treatment and supportive care, pulmonary complications remain the leading cause of morbidity and mortality in individuals with cystic fibrosis. Airway clearance therapy is a fundamental component of respiratory management in patients with CF. The primary objective of airway clearance techniques (ACTs) is to mobilize and remove retained airway secretions, thereby improving ventilation, reducing airway obstruction, minimizing infection risk, preserving lung function, and enhancing quality of life. Various ACTs are available and are routinely incorporated into multidisciplinary CF care programs. However, determining the most effective airway clearance strategy remains challenging because patient responses vary and comparative evidence among techniques is often limited. Autogenic drainage (AD) is an airway clearance technique based on controlled breathing at different lung volumes. The technique consists of three phases: unsticking, collecting, and evacuating secretions. Through carefully regulated inspiratory and expiratory airflow, AD promotes mucus mobilization from peripheral airways toward central airways where it can be effectively expectorated. Because the technique relies on self-regulated breathing rather than external mechanical forces, it may improve patient comfort, encourage independence, and facilitate long-term adheren

数据加载示例(图像类)

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

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