脑生化表型的全基因组关联研究揭示阿尔茨海默病相关蛋白的独特遗传结构

数据集获取

源站：https://synapse.org/Synapse:syn35564295

标准获取流程：

1. 访问源站链接，注册/登录账号；
2. 进入数据集详情页，按页面指引申请权限或直接下载；
3. 部分平台提供 SDK，例如：
   • OpenDataLab: pip install openxlab 后 openxlab.dataset.get(...)
   • ModelScope: pip install modelscope 后 modelscope download
   • 天池: 登录后页面提供直链下载
     以源站「数据下载/使用文档」页面为准。

数据说明

Manuscript: Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer’s Disease related proteins Authors: Stephanie R. Oatman*, Joseph S. Reddy*, Zachary Quicksall, Minerva M. Carrasquillo, Xue Wang, Chia-Chen Liu, Yu Yamazaki, Thuy T. Nguyen, Kimberly Malphrus, Michael Heckman, Kristi Biswas, Kwangsik Nho, Matthew Baker, Yuka A. Martens, Na Zhao, Jun Pyo Kim, Shannon Risacher, Rosa Rademakers, Andrew Saykin, Michael DeTure, Melissa E. Murray, Takahisa Kanekiyo, for the Alzheimer’s Disease Neuroimaging Initiative, Dennis W. Dickson, Guojun Bu, Mariet Allen, Nilüfer Ertekin-Taner Preprint URL: https://www.biorxiv.org/content/10.1101/2022.05.31.493731v1 Published URL: https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-022-00592-2 Dataset contact: Dr. Nilüfer Ertekin-Taner, Mayo Clinic @net04; Adriana Mitchell, Mayo Clinic @adrianami Webinar Recording: https://news.adknowledgeportal.org/webinars/ — Data use acknowledgement: Please acknowledge the data contributor in publications based on secondary data use by including the following statement and references in your manuscript. >"The results published here are in whole or in part based on data obtained from the AD Knowledge Portal (https://adknowledgeportal.org/). " >Mayo Clinic AD-CAA: “The Mayo Clinic AD-CAA study was led by Dr. Guojun Bu and Dr. Nilufer Ertekin-Taner at Mayo Clinic, Jacksonville, FL as part of the multi-PI RF1AG051504 (MPIs Bu and Ertekin-Taner) using samples from the Mayo Clinic Brain Bank. Data collection was supported through funding by NIA grants P50AG016574, R37AG027924, Cure Alzheimer’s Fund, and support from Mayo Foundation.” Cite: doi: 10.7303/syn2580853 >Mayo RNAseq: "The Mayo RNAseq study data was led by Dr. Nilüfer Ertekin-Taner, Mayo Clinic, Jacksonville, FL as part of the multi-PI U01 AG046139 (MPIs Golde, Ertekin-Taner, Younkin, Price). Samples were provided fro

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。