Treo/Flu/TBI联合供体干细胞移植治疗骨髓增生异常综合征或急性髓系白血病
该数据集来自clinicaltrials.gov,聚焦于Treo/Flu/TBI联合供体干细胞移植治疗骨髓增生异常综合征或急性髓系白血病

基本信息
资源简介
Treo/Flu/TBI联合供体干细胞移植治疗骨髓增生异常综合征或急性髓系白血病
该数据集来自clinicaltrials.gov,聚焦于Treo/Flu/TBI联合供体干细胞移植治疗骨髓增生异常综合征或急性髓系白血病。覆盖急性髓系白血病缓解期、慢性粒单核细胞白血病、微小残留病、骨髓增生异常综合征及骨髓增生异常/骨髓增殖性肿瘤等疾病状态。数据可用于比较两种基于treosulfan的预处理方案,评估6个月无进展生存期,并分析基因表达谱变化与疾病复发关联,以及移植后1年、2年的无进展生存率和总生存率等结局(来源 clinicaltrials.gov)。
【数据内容】
源站描述(机器翻译,仅供参考):条件:急性髓系白血病缓解期、慢性粒单核细胞白血病、微小残留病、骨髓增生异常综合征、骨髓增生异常/骨髓增殖性肿瘤、骨髓增生异常/骨髓增殖性肿瘤,不可分类。主要目标:I. 通过比较6个月无进展生存期,确定两种基于treosulfan的预处理方案在骨髓增生异常综合征(MDS)和急性髓系白血病(AML)患者中哪种更优。次要目标:I. 确定两种预处理方案对基因表达谱变化的影响,并评估基因表达谱与疾病复发的关联。II. 确定造血细胞移植(HCT)后1年和2年无进展生存期的发生率。III. 评估HCT后6个月、1年和2年的总生存期(OS)。IV. 确定
【主题与分类】
主题标签:Acute Myeloid Leukemia in Remission、Chronic Myelomonocytic Leukemia、Minimal Residual Disease、Myelodysplastic Syndrome。本站分类:肿瘤/白血病。
【获取与许可】
源站页面:https://clinicaltrials.gov/study/NCT01894477
下载信息
注册下载
需要注册 Kaggle 账号并登录后下载,适合需要跟踪下载记录和使用 API 的用户。
暂未开放公开下载
无需注册即可直接获取公开样本或文档,适合快速预览和评估数据集质量。
免登录有偿下载
公开数据集受托下载与技术交付服务。
提供高速下载与技术交付服务(收技术服务费,非数据销售)
暂未开放当前数据集主要来源为 Kaggle 公开托管,完整影像包建议通过原始链接或 Kaggle API 获取。
使用方式
数据集获取
源站:https://clinicaltrials.gov/study/NCT01894477
标准获取流程:
- 访问源站链接,注册/登录账号;
- 进入数据集详情页,按页面指引申请权限或直接下载;
- 部分平台提供 SDK,例如:
- OpenDataLab:
pip install openxlab后openxlab.dataset.get(...) - ModelScope:
pip install modelscope后modelscope download - 天池: 登录后页面提供直链下载
以源站「数据下载/使用文档」页面为准。
- OpenDataLab:
数据说明
Conditions: Acute Myeloid Leukemia in Remission, Chronic Myelomonocytic Leukemia, Minimal Residual Disease, Myelodysplastic Syndrome, Myelodysplastic/Myeloproliferative Neoplasm, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable. PRIMARY OBJECTIVES: I. To determine the better of two treosulfan-based conditioning regimens in patients with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), by comparing 6-month progression-free survival. SECONDARY OBJECTIVES: I. Determine the effects of two conditioning regimens on changes in gene expression profiles, and evaluate the association of gene expression profiles and disease relapse. II. Determine the incidence of progression-free survival at 1 year and 2 years after hematopoietic cell transplantation (HCT). III. Evaluate overall survival (OS) at 6 months, at 1 year and at 2 years after HCT. IV. Determine the incidence of grades II-IV acute graft-versus-host disease (GVHD). V. Determine the incidence of chronic GVHD. VI. Determine donor chimerism around days +28 and +84. CONDITIONING REGIMEN: Arm A: Patients receive treosulfan intravenously (IV) over 2 hours on days -6 to -4 and fludarabine phosphate IV over 30 minutes on days -6 to -2. Arm B: Patients receive treosulfan and fludarabine phosphate as in Arm A and undergo low-dose total-body irradiation (TBI) on day 0. TRANSPLANT: Patients in both arms undergo allogeneic peripheral blood stem cell (PBSC) transplant or bone marrow transplant on day 0. GVHD PROPHYLAXIS: Patients with a related donor receive tacrolimus orally (PO) every 8 or 12 hours on days -3 to 56 with taper to day 180. Beginning 4-6 hours after PBSC infusion, patients also receive mycophenolate mofetil PO every 12 hours to day 28. Patients with an unrelated donor receive tacrolimus PO every 8 or 12 hours on days -3 to 100 with taper to day 180. Beginning 4-6 hours after PBSC infusion, patients also receive mycophenolate mofetil PO every 8 hours to day 40 with taper to day 96. NOTE: Patients with related donors eligible for FHCRC protocol 2545 may receive cyclosporine IV, instead of tacrolimus, beginning on day -3 to day 50 with a taper to day 180. After completion of study treatmen
数据加载示例(图像类)
from PIL import Image
import glob, os
files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
+ glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
+ glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)
# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path) # 要求 子目录=类别
目录组织与标注格式以源站说明和下载后实际文件为准。
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