BMP信号拮抗剂Noggin在前列腺癌溶骨性骨转移发展中的作用

资源简介

BMP信号拮抗剂Noggin在前列腺癌溶骨性骨转移发展中的作用

【数据集背景】

本数据集源站标题为《The Role of the BMP Signaling Antagonist Noggin in the Development of Prostate Cancer Osteolytic Bone Metastasis》。配套论文《The Role of the BMP Signaling Antagonist Noggin in the Development of Prostate Cancer Osteolytic Bone Metastasis》发表于 PLoS ONE（2011），DOI：10.1371/journal.pone.0016078。源站首次发布：2011-01-13。

【数据内容】

源站原始描述：Members of the BMP and Wnt protein families play a relevant role in physiologic and pathologic bone turnover. Extracellular antagonists are crucial for the modulation of their activity. Lack of expression of the BMP antagonist noggin by osteoinductive, carcinoma-derived cell lines is a determinant of the osteoblast response induced by their bone metastases. In contrast, osteolytic, carcinoma-derived cell lines express noggin constitutively. We hypothesized that cancer cell-derived noggin may con…

【数据结构与技术规格】

文件数 5 个，合计 4.57 MB。Figure_S1.tif：image/tiff，890.89 KB。Figure_S2.tif：image/tiff，2.61 MB。Figure_S3.tif：image/tiff，1.03 MB。数据集 DOI：10.1371/journal.pone.0016078。

【主题与分类】

源站学科分类：Physiology、Cancer。主题标签：bmp、signaling、antagonist、noggin、prostate、cancer、osteolytic、metastasis。

【适用方向】

源站学科分类标注为 Physiology、Cancer。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/The_Role_of_the_BMP_Signaling_Antagonist_Noggin_in_the_Development_of_Prostate_Cancer_Osteolytic_Bone_Metastasis/139585

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Secondini, Chiara; Wetterwald, Antoinette; Schwaninger, Ruth; N. Thalmann, George; G. Cecchini, Marco (2016). The Role of the BMP Signaling Antagonist Noggin in the Development of Prostate Cancer Osteolytic Bone Metastasis. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-30，引用时请注意版本时效。