抗TGFβ抗体在多柔比星介导的乳腺癌骨转移骨丢失中的挽救作用数据集

资源简介

抗TGFβ抗体在多柔比星介导的乳腺癌骨转移骨丢失中的挽救作用数据集

【数据集背景】

本数据集源站标题为《Anti-TGFβ antibody rescues doxorubicin mediated bone loss in breast cancer bone metastasis.》。配套论文《Doxorubicin-Mediated Bone Loss in Breast Cancer Bone Metastases Is Driven by an Interplay between Oxidative Stress and Induction of TGFβ》发表于 PLoS ONE（2013），DOI：10.1371/journal.pone.0078043。源站首次发布：2013-10-30。

【数据内容】

源站原始描述：MDA-MB-231 cells (1×106) were inoculated via left cardiac ventricle of four-week old female athymic nude mice and treated with PBS, doxorubicin (5 mg/Kg, once weekly for 4 weeks, i.p.), 1D11 (10 mg/Kg, three times per weekly for 4 weeks) and a combination of doxorubicin and 1D11 for three weeks. (A) Representative microCT images of mice tibiae from each treatment group (B) Quantification of trabecular bone volume (BV/TV), (C) Histology of mice tibia from each group revealed trabecular bone loss…

【数据结构与技术规格】

文件数 1 个，合计 4.22 MB。Figure 4.tif：image/tiff，4.22 MB。数据集 DOI：10.1371/journal.pone.0078043.g004。

【主题与分类】

源站学科分类：Medicine、Cell Biology、Genetics、Physiology、Environmental Sciences not elsewhere classified、Ecology。主题标签：NAC、trabecular bone volume、BV、TGF β、breast cancer bone metastasis model、osteolytic bone damage、antibody、osteolytic lesion areas、SOD、doxorubicin treatment increases。

【适用方向】

源站学科分类标注为 Medicine、Cell Biology、Genetics、Physiology、Environmental Sciences not elsewhere classified、Ecology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Anti_TGF_946_antibody_rescues_doxorubicin_mediated_bone_loss_in_breast_cancer_bone_metastasis_/837189

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Rana, Tapasi; Chakrabarti, Anwesa; Freeman, Michael; Biswas, Swati (2016). Anti-TGFβ antibody rescues doxorubicin mediated bone loss in breast cancer bone metastasis.. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-05，引用时请注意版本时效。