TAp63通过调控TNFRSF11B/骨保护素表达调节骨重塑

资源简介

TAp63通过调控TNFRSF11B/骨保护素表达调节骨重塑

【数据集背景】

本数据集源站标题为《TAp63 regulates bone remodeling by modulating the expression of TNFRSF11B/Osteoprotegerin》。配套论文《TAp63 regulates bone remodeling by modulating the expression of TNFRSF11B/Osteoprotegerin》发表于 Cell Cycle（2021），DOI：10.1080/15384101.2021.1985772。项目资助方：This work was supported by the Ministero della Salute [#PGR00961].。源站首次发布：2021-11-12。

【数据内容】

源站原始描述：The transcription factor p53 has been shown to control the differentiation process of the mesenchymal stem cells (MSCs). As a matter of fact, in vivo p53 loss leads to an unbalance between bone formation versus bone erosion. Using as experimental system, human bone marrow-derived MSCs and mouse bone marrow-derived TAp63-/- MSCs, we have asked whether the other members of the p53 family, p63 and p73, are involved in controlling MSCs osteogenic differentiation. Our results indicate that both durin…

【数据结构与技术规格】

文件数 2 个，合计 662.05 KB。Lena et al - Suppl Table S1-S2-S3.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，14.15 KB。Supplementary figures.pdf：application/pdf，647.90 KB。数据集 DOI：10.6084/m9.figshare.16995138.v1。

【主题与分类】

源站学科分类：Biochemistry、Cell Biology、Genetics、Physiology、Biotechnology、Ecology。主题标签：P63、p53 family、mesenchymal stem cells、osteogenic differentiation、breast、prostate cancer。

【适用方向】

源站学科分类标注为 Biochemistry、Cell Biology、Genetics、Physiology、Biotechnology、Ecology。

【获取与许可】

源站页面：https://tandf.figshare.com/articles/dataset/TAp63_regulates_bone_remodeling_by_modulating_the_expression_of_TNFRSF11B_Osteoprotegerin/16995138

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：TAp63 regulates bone remodeling by modulating the expression of TNFRSF11B/Osteoprotegerin. Taylor & Francis. Lena, Anna Maria; Foffi, Erica; Agostini, Massimiliano; Mancini, Mara; Annicchiarico-Petruzzelli, Margherita; Aberdam, Daniel; et al

【使用注意】

· 源站最后修改于 2024-07-04，引用时请注意版本时效。