RS4;11细胞系作为t(4;11)(q21;q23)白血病模型的细胞遗传学特征修订

资源简介

RS4;11细胞系作为t(4;11)(q21;q23)白血病模型的细胞遗传学特征修订

【数据集背景】

本数据集源站标题为《The RS4;11 cell line as a model for leukaemia with t(4;11)(q21;q23): revised characterisation of cytogenetics features》。源站首次发布：2019-06-03。

【数据内容】

源站原始描述：Figure 1. Representative karyotype of RS4;11 obtained by M-FISH. In this metaphase the karyotype was determined to be 46,XX,t(4;11)(q21;q23),i(7)(q10),i(8)(q10). Arrows indicate the derivatives der(4) and der(11), i(7q) and i(8q). Figure 2. Cytogenetic abnormalities investigated by FISH in the RS4;11 cell line. (A-B) Whole chromosome paints for chromosomes X and 18 did not reveal any numerical abnormalities. (C-D) An isochromosome 7q was detected using an arm-specific probe (long arm in red and…

【数据结构与技术规格】

文件数 4 个，合计 3.20 MB。Figure 1.tif：image/tiff，314.35 KB。Figure 2.tif：image/tiff，1.93 MB。Figure 3.tif：image/tiff，453.05 KB。数据集 DOI：10.17633/rd.brunel.8016191.v1。

【主题与分类】

源站学科分类：Genetics not elsewhere classified、Haematology、Oncology and carcinogenesis not elsewhere classified。主题标签：Leukaemia、Leukaemia cell line、RS4;11、Fluorescence in situ Hybridisation、M-FISH、karyotype、RT-PCR、fusion transcript、MLL gene、MLL-AF4。

【适用方向】

源站学科分类标注为 Genetics not elsewhere classified、Haematology、Oncology and carcinogenesis not elsewhere classified。

【获取与许可】

源站页面：https://brunel.figshare.com/articles/dataset/The_RS4_11_cell_line_as_a_model_for_leukaemia_with_t_4_11_q21_q23_revised_characterisation_of_cytogenetics_features/8016191

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：ragusa, Denise; Makarov, Evgeny; Britten, Oliver; Moralli, Daniela; Green, catherine; Tosi, Sabrina (2019). The RS4;11 cell line as a model for leukaemia with t(4;11)(q21;q23): revised characterisation of cytogenetics features. Brunel University London. Dataset