CERKL基因敲低导致斑马鱼视网膜变性

资源简介

CERKL基因敲低导致斑马鱼视网膜变性

【数据集背景】

本数据集源站标题为《CERKL Knockdown Causes Retinal Degeneration in Zebrafish》。配套论文《CERKL Knockdown Causes Retinal Degeneration in Zebrafish》发表于 PLoS ONE（2013），DOI：10.1371/journal.pone.0064048。源站首次发布：2013-05-09。

【数据内容】

源站原始描述：The human CERKL gene is responsible for common and severe forms of retinal dystrophies. Despite intense in vitro studies at the molecular and cellular level and in vivo analyses of the retina of murine knockout models, CERKL function remains unknown. In this study, we aimed to approach the developmental and functional features of cerkl in Danio rerio within an Evo-Devo framework. We show that gene expression increases from early developmental stages until the formation of the retina in the optic…

【数据结构与技术规格】

文件数 5 个，合计 1.79 MB。Figure_S1.tif：image/tiff，512.72 KB。Figure_S2.tif：image/tiff，650.17 KB。Figure_S3.tif：image/tiff，591.43 KB。数据集 DOI：10.1371/journal.pone.0064048。

【主题与分类】

源站学科分类：Medicine、Biological Sciences。主题标签：Evolutionary biology、Comparative genomics、Evolutionary developmental biology、Evolutionary genetics、genetics、Animal genetics、Gene function、Gene splicing、Genetics of disease、Model organisms。

【适用方向】

源站学科分类标注为 Medicine、Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_CERKL_Knockdown_Causes_Retinal_Degeneration_in_Zebrafish/701151

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Riera, Marina; Burguera, Demian; Garcia-Fernàndez, Jordi; Gonzàlez-Duarte, Roser (2016). CERKL Knockdown Causes Retinal Degeneration in Zebrafish. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。