膜蛋白半胱氨酸突变细胞表面运输修复数据集

资源简介

膜蛋白半胱氨酸突变细胞表面运输修复数据集

【数据集背景】

本数据集源站标题为《Restoration of Proper Trafficking to the Cell Surface for Membrane Proteins Harboring Cysteine Mutations》。配套论文《Restoration of Proper Trafficking to the Cell Surface for Membrane Proteins Harboring Cysteine Mutations》发表于 PLoS ONE（2012），DOI：10.1371/journal.pone.0047693。源站首次发布：2012-10-17。

【数据内容】

源站原始描述：A common phenotype for many genetic diseases is that the cell is unable to deliver full-length membrane proteins to the cell surface. For some forms of autism, hereditary spherocytosis and color blindness, the culprits are single point mutations to cysteine. We have studied two inheritable cysteine mutants of cyclic nucleotide-gated channels that produce achromatopsia, a common form of severe color blindness. By taking advantage of the reactivity of cysteine’s sulfhydryl group, we modified these…

【数据结构与技术规格】

文件数 2 个，合计 1.85 MB。Figure_S1.tif：image/tiff，583.41 KB。Figure_S2.tif：image/tiff，1.27 MB。数据集 DOI：10.1371/journal.pone.0047693。

【主题与分类】

源站学科分类：Biochemistry、Biophysics、Medicine。主题标签：restoration、trafficking、membrane、proteins、harboring、cysteine、mutations。

【适用方向】

源站学科分类标注为 Biochemistry、Biophysics、Medicine。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Restoration_of_Proper_Trafficking_to_the_Cell_Surface_for_Membrane_Proteins_Harboring_Cysteine_Mutations/118329

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Lopez-Rodriguez, Angelica; Holmgren, Miguel (2016). Restoration of Proper Trafficking to the Cell Surface for Membrane Proteins Harboring Cysteine Mutations. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-05，引用时请注意版本时效。