人类非酒精性脂肪性肝炎中补体替代途径的激活

资源简介

人类非酒精性脂肪性肝炎中补体替代途径的激活

【数据集背景】

本数据集源站标题为《Complement Alternative Pathway Activation in Human Nonalcoholic Steatohepatitis》。配套论文《Complement Alternative Pathway Activation in Human Nonalcoholic Steatohepatitis》发表于 PLoS ONE（2014），DOI：10.1371/journal.pone.0110053。源站首次发布：2014-10-09。

【数据内容】

源站原始描述：The innate immune system plays a major role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Recently we reported complement activation in human NASH. However, it remained unclear whether the alternative pathway of complement, which amplifies C3 activation and which is frequently associated with pathological complement activation leading to disease, was involved. Here, alternative pathway components were investigated in liver biopsies of obese subjects with healthy livers (n = 10) or…

【数据结构与技术规格】

文件数 2 个，合计 68.10 KB。Table_S1.doc：application/msword，32.77 KB。Table_S2.doc：application/msword，35.33 KB。数据集 DOI：10.1371/journal.pone.0110053。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：alternative pathway activation、complement activation、C 3 activation、pcr、C 3 activation product C 3c C 3 activation status、subject、C 3c C 3 ratio、factor H mRNA、Decay Accelerating Factor、nash。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Complement_Alternative_Pathway_Activation_in_Human_Nonalcoholic_Steatohepatitis_/1199727

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：M. Segers, Filip; J. Verdam, Froukje; de Jonge, Charlotte; Boonen, Bas; Driessen, Ann; Shiri-Sverdlov, Ronit; et al. (2016). Complement Alternative Pathway Activation in Human Nonalcoholic Steatohepatitis. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-30，引用时请注意版本时效。