无柄锯齿状腺瘤/息肉的原始CpG岛甲基化表型

资源简介

无柄锯齿状腺瘤/息肉的原始CpG岛甲基化表型

【数据集背景】

本数据集源站标题为《The proto CpG island methylator phenotype of sessile serrated adenomas/polyps》。配套论文《The proto CpG island methylator phenotype of sessile serrated adenomas/polyps》发表于 Epigenetics（2018），DOI：10.1080/15592294.2018.1543504。项目资助方：Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung [310030-160163/1].。源站首次发布：2018-11-06。

【数据内容】

源站原始描述：Sessile serrated adenomas/polyps (SSA/Ps) are the putative precursors of the ~20% of colon cancers with the CpG island methylator phenotype (CIMP). To investigate the epigenetic phenotype of these precancers, we prospectively collected fresh-tissue samples of 17 SSA/Ps and 15 conventional adenomas (cADNs), each with a matched sample of normal mucosa. Their DNA was subjected to bisulfite next-generation sequencing to assess methylation levels at ~2.7 million CpGs located predominantly in gene reg…

【数据结构与技术规格】

文件数 13 个，合计 34.50 MB。Parker H et al_Supplementary Material.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，50.59 KB。SUPPLEMENTARY FIGURE 1.pdf：application/pdf，220.95 KB。SUPPLEMENTARY FIGURE 2.pdf：application/pdf，1.18 MB。数据集 DOI：10.6084/m9.figshare.7302227.v1。

【主题与分类】

源站学科分类：Biochemistry、Microbiology、Cell Biology、Genetics、Molecular Biology、Pharmacology。主题标签：Sessile serrated adenoma/polyp、adenomatous polyp、colon cancer、DNA methylation。

【适用方向】

源站学科分类标注为 Biochemistry、Microbiology、Cell Biology、Genetics、Molecular Biology、Pharmacology。

【获取与许可】

源站页面：https://tandf.figshare.com/articles/dataset/The_proto_CpG_island_methylator_phenotype_of_sessile_serrated_adenomas_polyps/7302227

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：The proto CpG island methylator phenotype of sessile serrated adenomas/polyps. Taylor & Francis. R. Parker, Hannah; Orjuela, Stephany; Oliveira, Andreia Martinho; Cereatti, Fabrizio; Sauter, Matthias; Heinrich, Henriette; et al

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。