衰老和基因突变小鼠二尖瓣瓣叶的多尺度生物力学重塑：马凡综合征的启示

资源简介

衰老和基因突变小鼠二尖瓣瓣叶的多尺度生物力学重塑：马凡综合征的启示

【数据集背景】

本数据集源站标题为《Multi-Scale Biomechanical Remodeling in Aging and Genetic Mutant Murine Mitral Valve Leaflets: Insights into Marfan Syndrome》。配套论文《Multi-Scale Biomechanical Remodeling in Aging and Genetic Mutant Murine Mitral Valve Leaflets: Insights into Marfan Syndrome》发表于 PLoS ONE（2012），DOI：10.1371/journal.pone.0044639。源站首次发布：2012-09-11。

【数据内容】

源站原始描述：Mitral valve degeneration is a key component of the pathophysiology of Marfan syndrome. The biomechanical consequences of aging and genetic mutation in mitral valves are poorly understood because of limited tools to study this in mouse models. Our aim was to determine the global biomechanical and local cell-matrix deformation relationships in the aging and Marfan related Fbn1 mutated murine mitral valve. To conduct this investigation, a novel stretching apparatus and gripping method was implemen…

【数据结构与技术规格】

文件数 7 个，合计 7.85 MB。Figure_S1.tif：image/tiff，843.09 KB。Figure_S2.tif：image/tiff，1.13 MB。Figure_S3.tif：image/tiff，2.32 MB。数据集 DOI：10.1371/journal.pone.0044639。

【主题与分类】

源站学科分类：Physics、Biotechnology、Genetics。主题标签：multi-scale、biomechanical、remodeling、aging、mutant、murine、mitral、valve、insights、marfan。

【适用方向】

源站学科分类标注为 Physics、Biotechnology、Genetics。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Multi_Scale_Biomechanical_Remodeling_in_Aging_and_Genetic_Mutant_Murine_Mitral_Valve_Leaflets_Insights_into_Marfan_Syndrome/120351

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：A. Gould, Russell; Sinha, Ravi; Aziz, Hamza; Rouf, Rosanne; C. Dietz III, Harry; P. Judge, Daniel; et al. (2016). Multi-Scale Biomechanical Remodeling in Aging and Genetic Mutant Murine Mitral Valve Leaflets: Insights into Marfan Syndrome. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。