多梳介导的抑制与声波刺猬信号相互作用调控皮肤发育过程中的默克尔细胞特化

资源简介

多梳介导的抑制与声波刺猬信号相互作用调控皮肤发育过程中的默克尔细胞特化

【数据集背景】

本数据集源站标题为《Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development》。配套论文《Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development》发表于 PLOS Genetics（2016），DOI：10.1371/journal.pgen.1006151。源站首次发布：2016-07-14。

【数据内容】

源站原始描述：An increasing amount of evidence indicates that developmental programs are tightly regulated by the complex interplay between signaling pathways, as well as transcriptional and epigenetic processes. Here, we have uncovered coordination between transcriptional and morphogen cues to specify Merkel cells, poorly understood skin cells that mediate light touch sensations. In murine dorsal skin, Merkel cells are part of touch domes, which are skin structures consisting of specialized keratinocytes, Me…

【数据结构与技术规格】

文件数 8 个，合计 95.24 MB。数据集 DOI：10.1371/journal.pgen.1006151。

【主题与分类】

源站学科分类：Cell Biology、Genetics、Molecular Biology、Physiology、Immunology、Developmental Biology。主题标签：Merkel cell specification、murine dorsal skin、hair follicle functions、morphogen cues、skin structures、PRC 2 targets、Merkel cell differentiation program、ectopic Merkel cells、PRC 2 loss、light touch sensations。

【适用方向】

源站学科分类标注为 Cell Biology、Genetics、Molecular Biology、Physiology、Immunology、Developmental Biology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Polycomb-Mediated_Repression_and_Sonic_Hedgehog_Signaling_Interact_to_Regulate_Merkel_Cell_Specification_during_Skin_Development/3897816

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Perdigoto, Carolina N.; Dauber, Katherine L.; Bar, Carmit; Tsai, Pai-Chi; J. Valdes, Victor; Cohen, Idan; et al. (2016). Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. PLOS Genetics. Dataset

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。