人羊膜间充质干细胞治疗钙化防御症患者皮肤病变及转移性肺钙化的疗效——病例系列与文献综述数据集

Name: 人羊膜间充质干细胞治疗钙化防御症患者皮肤病变及转移性肺钙化的疗效——病例系列与文献综述数据集
Creator: Lv, Xiaolin; Ye, Xiaoxue; Xing, Changying; Liu, Wei; Li, Cui; Zhang, Ling; Wu, Jingjing; Wang, Ningning; Jiang, Chunyan; Yuan, Yanggang; Qin, Lianju; Xu, Yi; Yang, Jiahui; Su, Zhonglan; Li, Fan; Bian, Anning; Wang, Xiuqin; Liang, Ningxia; Ouyang, Chun; Ning, Song; Cui, Yugui; Ma, Xiang; Hu, Jiaying; Liu, Jiayin; Cui, Hongqing; Lu, Yan; Wang, Ling; Lu, Shijiu; Zeng, Ming
License: CC BY 4.0

该数据集包含3名钙化防御症合并转移性肺钙化患者的临床病例资料，数据模态涵盖临床评估量表（如VAS、BWAT-CUA、Wound-QoL）、组织学分析以及影像学检查结果（包括HRCT、99mTc-MDP骨扫描和首次应用的99mTc-MAA肺灌注成像）。其主要用途是评估人羊膜间充质干细胞治疗对患者皮肤病变愈合和肺部钙化进展的疗效，为这一罕见致命疾病的个性化再生治疗策略提供研究依据和临床参考。

Lv, Xiaolin; Ye, Xiaoxue; Xing, Changying; Liu, Wei; Li, Cui; Zhang, Ling; Wu, Jingjing; Wang, Ningning; Jiang, Chunyan; Yuan, Yanggang; Qin, Lianju; Xu, Yi; Yang, Jiahui; Su, Zhonglan; Li, Fan; Bian, Anning; Wang, Xiuqin; Liang, Ningxia; Ouyang, Chun; Ning, Song; Cui, Yugui; Ma, Xiang; Hu, Jiaying; Liu, Jiayin; Cui, Hongqing; Lu, Yan; Wang, Ling; Lu, Shijiu; Zeng, Ming

Taylor & Francis Group

2025-07-08 更新

Calciphylaxiscalcific uremic arteriolopathymetastatic pulmonary calcification99ᵐTc-MDP99ᵐTc-MAA pulmonary perfusion imaging

Treatment effects of human amnion-derived mesenchymal stem cells for skin lesions and metastatic pulmonary calcification in calciphylaxis patients – case series and literature review

基本信息

大小

0.027761267 GB

许可

CC BY 4.0

创建/更新时间

2025-07-08

版本

资源简介

人羊膜间充质干细胞治疗钙化防御症患者皮肤病变及转移性肺钙化的疗效——病例系列与文献综述数据集

【数据集背景】

本数据集源站标题为《Treatment effects of human amnion-derived mesenchymal stem cells for skin lesions and metastatic pulmonary calcification in calciphylaxis patients – case series and literature review》。配套论文《Treatment effects of human amnion-derived mesenchymal stem cells for skin lesions and metastatic pulmonary calcification in calciphylaxis patients – case series and literature review》发表于 Renal Failure（2025），DOI：10.1080/0886022X.2025.2516207。项目资助方：This study was funded by the National Natural Science Foundation of China (81270408, 81570666, 81730041, and 81671447), the International Society of Nephrology (ISN) Clinical Research Program (18-01-0247), Jiangsu Province Key Medical Personnel Project (ZDRCA2016002), CKD Anemia Research Foundation from China International Medical Foundation (Z-2017-24-2037), Outstanding Young and Middle-Aged Talents Support Program of the First Affiliated Hospital with Nanjing Medical University, the National Key Research and Development Program of China (2017YFC1001303), the Program of Jiangsu Province Clinical Medical Center (YXZXB2016001, BL2012009), the State Key Laboratory of Reproductive Medicine Program (SKLRM-GC201803), Jiangsu Province Hospital Clinical Capacity Enhancement Project (JSPH-MA-2023-7), Specialized Diseases Clinical Research Fund of Jiangsu Province Hospital (XB202403), Key Projects of Medical Scientific Research Funded by the Health Commission of Jiangsu Province (K2024005), and the Program of Jiangsu Provincial Medical Key Discipline(Laboratory) Cultivation Unit (JSDW202206).。源站首次发布：2025-07-08。

【数据内容】

源站原始描述：Calciphylaxis, also termed calcific uremic arteriolopathy (CUA) in patients with end-stage kidney disease (ESKD), is a rare and fatal condition characterized by cutaneous ischemic necrosis. Three patients with calciphylaxis and metastatic pulmonary calcification (MPC) were treated with human amnion-derived mesenchymal stem cells (hAMSCs). Effects were evaluated using the Visual Analogue Scale (VAS), modified Bates-Jensen Wound Assessment Tool for CUA (BWAT-CUA), wound quality of life questionnai…

【数据结构与技术规格】

文件数 4 个，合计 27.76 MB。irnf_a_2516207_sm6246.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，18.87 KB。irnf_a_2516207_sm9358.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，15.59 KB。irnf_a_2516207_sm9356.png：image/png，291.36 KB。数据集 DOI：10.6084/m9.figshare.29323957.v2。

【主题与分类】

源站学科分类：Medicine、Cell Biology、Physiology、Chemical Sciences not elsewhere classified、Immunology、Biological Sciences not elsewhere classified。主题标签：Calciphylaxis、calcific uremic arteriolopathy、metastatic pulmonary calcification、99ᵐTc-MDP、99ᵐTc-MAA pulmonary perfusion imaging、human amnion-derived mesenchymal stem cells。

【适用方向】

源站学科分类标注为 Medicine、Cell Biology、Physiology、Chemical Sciences not elsewhere classified、Immunology、Biological Sciences not elsewhere classified。

【获取与许可】

源站页面：https://tandf.figshare.com/articles/dataset/Treatment_effects_of_human_amnion-derived_mesenchymal_stem_cells_for_skin_lesions_and_metastatic_pulmonary_calcification_in_calciphylaxis_patients_case_series_and_literature_review/29323957

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Treatment effects of human amnion-derived mesenchymal stem cells for skin lesions and metastatic pulmonary calcification in calciphylaxis patients – case series and literature review. Taylor & Francis. Lu, Shijiu; Zeng, Ming; Li, Fan; Ouyang, Chun; Wu, Jingjing; Hu, Jiaying; et al

【使用注意】

· 源站最后修改于 2026-09-15，引用时请注意版本时效。

原始链接

https://tandf.figshare.com/articles/dataset/Treatment_effects_of_human_amnion-derived_mesenchymal_stem_cells_for_skin_lesions_and_metastatic_pulmonary_calcification_in_calciphylaxis_patients_case_series_and_literature_review/29323957/2

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源站：https://tandf.figshare.com/articles/dataset/Treatment_effects_of_human_amnion-derived_mesenchymal_stem_cells_for_skin_lesions_and_metastatic_pulmonary_calcification_in_calciphylaxis_patients_case_series_and_literature_review/29323957/2

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数据说明

该数据集是一项关于人羊膜来源间充质干细胞（hAMSCs）治疗钙化防御症（又称钙化性尿毒症性小动脉病）患者皮肤病变和转移性肺钙化（MPC）的临床病例研究数据集。数据来源于对3名钙化防御症合并MPC患者的治疗过程，包含临床评估指标（如视觉模拟评分VAS、改良Bates-Jensen伤口评估工具BWAT-CUA、伤口生活质量问卷Wound-QoL）、组织学分析结果，以及影像学检查数据（高分辨率CT、99mTc-MDP骨扫描、首次应用于MPC患者的99mTc-MAA肺灌注成像）。数据集记录了患者皮肤症状改善、伤口愈合情况以及MPC的影像学演变，旨在评估hAMSCs对皮肤和肺部病变的疗效，为钙化防御症的早期无创诊断和再生治疗提供临床依据。