PTCH1+/- 戈林综合征患者健康皮肤来源的皮肤成纤维细胞表现出癌相关成纤维细胞特征

资源简介

PTCH1+/- 戈林综合征患者健康皮肤来源的皮肤成纤维细胞表现出癌相关成纤维细胞特征

【数据集背景】

本数据集源站标题为《PTCH1+/− Dermal Fibroblasts Isolated from Healthy Skin of Gorlin Syndrome Patients Exhibit Features of Carcinoma Associated Fibroblasts》。配套论文《PTCH1+/− Dermal Fibroblasts Isolated from Healthy Skin of Gorlin Syndrome Patients Exhibit Features of Carcinoma Associated Fibroblasts》发表于 PLoS ONE（2009），DOI：10.1371/journal.pone.0004818。源站首次发布：2009-03-16。

【数据内容】

源站原始描述：Gorlin''s or nevoid basal cell carcinoma syndrome (NBCCS) causes predisposition to basal cell carcinoma (BCC), the commonest cancer in adult human. Mutations in the tumor suppressor gene PTCH1 are responsible for this autosomal dominant syndrome. In NBCCS patients, as in the general population, ultraviolet exposure is a major risk factor for BCC development. However these patients also develop BCCs in sun-protected areas of the skin, suggesting the existence of other mechanisms for BCC predisposi…

【数据结构与技术规格】

文件数 5 个，合计 53.48 KB。Figure_S1.pdf：application/pdf，14.64 KB。Table_S1.pdf：application/pdf，17.02 KB。Table_S2.pdf：application/pdf，6.45 KB。数据集 DOI：10.1371/journal.pone.0004818。

【主题与分类】

源站学科分类：Genetics、Cancer、Medicine。主题标签：dermal、fibroblasts、gorlin、patients、features、carcinoma。

【适用方向】

源站学科分类标注为 Genetics、Cancer、Medicine。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_PTCH1__Dermal_Fibroblasts_Isolated_from_Healthy_Skin_of_Gorlin_Syndrome_Patients_Exhibit_Features_of_Carcinoma_Associated_Fibroblasts/148201

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Valin, Alexandre; Barnay-Verdier, Stéphanie; Robert, Thomas; Ripoche, Hugues; Brellier, Florence; Chevallier-Lagente, Odile; et al. (2016). PTCH1+/− Dermal Fibroblasts Isolated from Healthy Skin of Gorlin Syndrome Patients Exhibit Features of Carcinoma Associated Fibroblasts. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。