皮肤巨噬细胞和树突状细胞耗竭促进小鼠基底细胞癌生长

资源简介

皮肤巨噬细胞和树突状细胞耗竭促进小鼠基底细胞癌生长

【数据集背景】

本数据集源站标题为《Depletion of Cutaneous Macrophages and Dendritic Cells Promotes Growth of Basal Cell Carcinoma in Mice》。配套论文《Depletion of Cutaneous Macrophages and Dendritic Cells Promotes Growth of Basal Cell Carcinoma in Mice》发表于 PLoS ONE（2014），DOI：10.1371/journal.pone.0093555。源站首次发布：2014-04-01。

【数据内容】

源站原始描述：Basal cell carcinoma (BCC) belongs to the group of non-melanoma skin tumors and is the most common tumor in the western world. BCC arises due to mutations in the tumor suppressor gene Patched1 (Ptch). Analysis of the conditional Ptch knockout mouse model for BCC reveals that macrophages and dendritic cells (DC) of the skin play an important role in BCC growth restraining processes. This is based on the observation that a clodronate-liposome mediated depletion of these cells in the tumor-bearing…

【数据结构与技术规格】

文件数 4 个，合计 4.91 MB。Figure_S1.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，750.93 KB。Figure_S2.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，2.64 MB。Figure_S3.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，1.50 MB。数据集 DOI：10.1371/journal.pone.0093555。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：cell biology、Signal transduction、cell signaling、Signaling cascades、Wnt signaling cascade、Molecular cell biology、dermatology、Skin neoplasms、Malignant skin neoplasms、Skin tumors。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Depletion_of_Cutaneous_Macrophages_and_Dendritic_Cells_Promotes_Growth_of_Basal_Cell_Carcinoma_in_Mice_/979546

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：König, Simone; Nitzki, Frauke; Uhmann, Anja; Dittmann, Kai; Theiss-Suennemann, Jennifer; Herrmann, Markus; et al. (2016). Depletion of Cutaneous Macrophages and Dendritic Cells Promotes Growth of Basal Cell Carcinoma in Mice. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。