全基因组关联研究确定HLA-DP为亚洲人群儿童哮喘易感基因

资源简介

全基因组关联研究确定HLA-DP为亚洲人群儿童哮喘易感基因

【数据集背景】

本数据集源站标题为《Genome-Wide Association Study Identifies HLA-DP as a Susceptibility Gene for Pediatric Asthma in Asian Populations》。配套论文《Genome-Wide Association Study Identifies HLA-DP as a Susceptibility Gene for Pediatric Asthma in Asian Populations》发表于 PLoS Genetics（2011），DOI：10.1371/journal.pgen.1002170。源站首次发布：2011-07-21。

【数据内容】

源站原始描述：Asthma is a complex phenotype influenced by genetic and environmental factors. We conducted a genome-wide association study (GWAS) with 938 Japanese pediatric asthma patients and 2,376 controls. Single-nucleotide polymorphisms (SNPs) showing strong associations (P−8) in GWAS were further genotyped in an independent Japanese samples (818 cases and 1,032 controls) and in Korean samples (835 cases and 421 controls). SNP rs987870, located between HLA-DPA1 and HLA-DPB1, was consistently associated wi…

【数据结构与技术规格】

文件数 5 个，合计 154.11 KB。Table_S1.xls：application/vnd.ms-excel，20.99 KB。Table_S2.xls：application/vnd.ms-excel，18.94 KB。Table_S3.xls：application/vnd.ms-excel，22.53 KB。数据集 DOI：10.1371/journal.pgen.1002170。

【主题与分类】

源站学科分类：Medicine、Genetics、Immunology。主题标签：genome-wide、identifies、susceptibility、pediatric、asthma、asian、populations。

【适用方向】

源站学科分类标注为 Medicine、Genetics、Immunology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Genome_Wide_Association_Study_Identifies_HLA_DP_as_a_Susceptibility_Gene_for_Pediatric_Asthma_in_Asian_Populations/134977

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Noguchi, Emiko; Sakamoto, Hiromi; Hirota, Tomomitsu; Ochiai, Kaori; Imoto, Yoshimasa; Sakashita, Masafumi; et al. (2016). Genome-Wide Association Study Identifies HLA-DP as a Susceptibility Gene for Pediatric Asthma in Asian Populations. PLOS Genetics. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。