脊索瘤临床前模型对BAF复合物抑制剂FHD-286（单用或与吉西他滨联用）不敏感

资源简介

脊索瘤临床前模型对BAF复合物抑制剂FHD-286（单用或与吉西他滨联用）不敏感

【数据集背景】

本数据集源站标题为《Chordoma preclinical models are insensitive to BAF complex inhibitor FHD-286, alone or in combination with gemcitabine》。源站首次发布：2025-07-29。

【数据内容】

源站原始描述：To evaluate BRG1(SMARCA4)/BRM(SMARCA2) as a potential therapeutic target, chordoma cell lines were treated with FHD-286. A panel of 4 chordoma cell lines were seeded in a white-walled 96-well plate so that at the start of treatment, 36 hours after plating, the confluence was 15%. The assay endpoint for each cell line was the amount of time for untreated cells to reach 80-90% confluence. Cell line-specific seeding densities and assay durations can be found through the link at the bottom of this p…

【数据结构与技术规格】

文件数 1 个，合计 212.92 KB。BAF_Complex_Inhibition_Illustrator_07292025.png：image/png，212.92 KB。数据集 DOI：10.6084/m9.figshare.28988870.v6。

【主题与分类】

源站学科分类：Cancer cell biology。主题标签：Chordoma、chordoma、Chordoma Foundation、CF Labs、Chordoma Foundation Lab、BAF、CH22、UM-Chor1、U-CH2、U-CHCF365。

【适用方向】

源站学科分类标注为 Cancer cell biology。

【获取与许可】

源站页面：https://figshare.com/articles/dataset/Chordoma_Preclinical_Models_Exhibit_Resistance_to_BAF_Complex_Inhibitor_FHD-286_Alone_or_in_Combination_with_Gemcitabine/28988870

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Foundation, Chordoma (2025). Chordoma preclinical models are insensitive to BAF complex inhibitor FHD-286, alone or in combination with gemcitabine. figshare. Dataset