视网膜母细胞瘤肿瘤抑制蛋白调控外源性物质解毒通路

资源简介

视网膜母细胞瘤肿瘤抑制蛋白调控外源性物质解毒通路

【数据集背景】

本数据集源站标题为《The Retinoblastoma Tumor Suppressor Regulates a Xenobiotic Detoxification Pathway》。配套论文《The Retinoblastoma Tumor Suppressor Regulates a Xenobiotic Detoxification Pathway》发表于 PLoS ONE（2011），DOI：10.1371/journal.pone.0026019。源站首次发布：2011-10-12。

【数据内容】

源站原始描述：The retinoblastoma tumor suppressor (pRb) regulates cell cycle entry, progression and exit by controlling the activity of the E2F-family of transcription factors. During cell cycle exit pRb acts as a transcriptional repressor by associating with E2F proteins and thereby inhibiting their ability to stimulate the expression of genes required for S phase. Indeed, many tumors harbor mutations in the RB gene and the pRb-E2F pathway is compromised in nearly all types of cancers. In this report we show…

【数据结构与技术规格】

文件数 3 个，合计 437.25 KB。Table_S1.doc：application/msword，153.60 KB。Table_S2.doc：application/msword，140.29 KB。Table_S3.doc：application/msword，143.36 KB。数据集 DOI：10.1371/journal.pone.0026019。

【主题与分类】

源站学科分类：Molecular Biology、Biological Sciences、Cancer、Genetics。主题标签：retinoblastoma、suppressor、regulates、xenobiotic、detoxification、pathway。

【适用方向】

源站学科分类标注为 Molecular Biology、Biological Sciences、Cancer、Genetics。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/The_Retinoblastoma_Tumor_Suppressor_Regulates_a_Xenobiotic_Detoxification_Pathway/132457

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Teresa Sáenz Robles, Maria; Case, Ashley; Chong, Jean-Leon; Leone, Gustavo; M. Pipas, James (2016). The Retinoblastoma Tumor Suppressor Regulates a Xenobiotic Detoxification Pathway. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-30，引用时请注意版本时效。