ERK1调控造血干细胞微环境

资源简介

ERK1调控造血干细胞微环境

【数据集背景】

本数据集源站标题为《ERK1 Regulates the Hematopoietic Stem Cell Niches》。配套论文《ERK1 Regulates the Hematopoietic Stem Cell Niches》发表于 PLoS ONE（2012），DOI：10.1371/journal.pone.0030788。源站首次发布：2012-01-30。

【数据内容】

源站原始描述：The mitogen-activated protein kinases (MAPK) ERK1 and ERK2 are among the major signal transduction molecules but little is known about their specific functions in vivo. ERK activity is provided by two isoforms, ERK1 and ERK2, which are ubiquitously expressed and share activators and substrates. However, there are not in vivo studies which have reported a role for ERK1 or ERK2 in HSCs and the bone marrow microenvironment. The present study shows that the ERK1-deficient mice present a mild osteope…

【数据结构与技术规格】

文件数 7 个，合计 1.43 MB。Figure_S1.tif：image/tiff，106.32 KB。Figure_S2.tif：image/tiff，110.56 KB。Figure_S3.tif：image/tiff，642.17 KB。数据集 DOI：10.1371/journal.pone.0030788。

【主题与分类】

源站学科分类：Molecular Biology、Developmental Biology。主题标签：erk1、regulates、hematopoietic、niches。

【适用方向】

源站学科分类标注为 Molecular Biology、Developmental Biology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/ERK1_Regulates_the_Hematopoietic_Stem_Cell_Niches/129236

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Saulnier, Nathalie; Guihard, Soizic; Holy, Xavier; Decembre, Elodie; Jurdic, Pierre; Clay, Denis; et al. (2016). ERK1 Regulates the Hematopoietic Stem Cell Niches. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。