表1_外周T细胞淋巴瘤基因组学及其对个性化医疗的意义
外周T细胞淋巴瘤基因组学及其个性化医疗意义的表格/综述文档。
基本信息
资源简介
表1_外周T细胞淋巴瘤基因组学及其对个性化医疗的意义
【一句话概览】
本数据集是 figshare 公开的结构化表格数据集，收录 1 个文件、合计 712.31 KB，主题涵盖 PTCL、AITL、ALCL、PTCL-NOS、genomics，可用于统计建模、特征工程与队列分析，CC BY 4.0 许可开放获取。
【数据集背景】
本数据集源站标题为《Table_1_Genomics of Peripheral T-Cell Lymphoma and Its Implications for Personalized Medicine.docx》。配套论文《International Peripheral T-Cell and Natural Killer/T-Cell Lymphoma Study: Pathology Findings and Clinical Outcomes》发表于 Journal of Clinical Oncology（2008），DOI：10.1200/JCO.2008.16.4558。源站首次发布：2020-06-19。
【数据内容】
源站原始描述：Peripheral T-cell lymphoma (PTCL) is a rare, heterogenous group of mature T-cell neoplasms that comprise 10–15% of non-Hodgkin lymphoma cases in the United States. All subtypes of PTCL, except for ALK+ anaplastic T-cell lymphoma, are associated with poor prognosis, with median overall survival (OS) rates of 1–3 years. The diagnosis of PTCL is mainly based on clinical presentation, morphologic features, and immunophenotypes. Recent advances in genome sequencing and gene expression profiling have…
【数据结构与技术规格】
文件数 1 个，合计 712.31 KB。Table_1_Genomics of Peripheral T-Cell Lymphoma and Its Implications for Personalized Medicine.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，712.31 KB。数据集 DOI：10.3389/fonc.2020.00898.s001。
【主题与分类】
源站学科分类：Cancer、Haematological Tumours、Radiation Therapy、Solid Tumours、Oncology and Carcinogenesis not elsewhere classified、Molecular Targets。主题标签：PTCL、AITL、ALCL、PTCL-NOS、genomics、personalized medicine、diagnosis、management。
【适用方向】
结构化表格数据可直接用于统计建模、特征工程与队列分析。
【获取与许可】
源站页面：https://frontiersin.figshare.com/articles/dataset/Table_1_Genomics_of_Peripheral_T-Cell_Lymphoma_and_Its_Implications_for_Personalized_Medicine_docx/12512039
使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。
规范引用：Zhang, Yumeng; Lee, Dasom; Brimer, Thomas; Hussaini, Mohammad; Sokol, Lubomir (2020). Table_1_Genomics of Peripheral T-Cell Lymphoma and Its Implications for Personalized Medicine.docx. Frontiers. Dataset
【使用注意】
· 源站最后修改于 2023-05-30，引用时请注意版本时效。
下载信息
注册下载
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免登录有偿下载
公开数据集受托下载与技术交付服务。
提供高速下载与技术交付服务（收技术服务费，非数据销售）
暂未开放当前数据集主要来源为 Kaggle 公开托管，完整影像包建议通过原始链接或 Kaggle API 获取。
使用方式
数据集获取（Figshare）
- 源站标题：Table_1_Genomics of Peripheral T-Cell Lymphoma and Its Implications for Personalized Medicine.docx
- DOI：10.3389/fonc.2020.00898.s001
- 发布日期：2020-06-19
- 文件数：1 个
- 文件总体积：712.31 KB
- 源站页面：https://frontiersin.figshare.com/articles/dataset/Table_1_Genomics_of_Peripheral_T-Cell_Lymphoma_and_Its_Implications_for_Personalized_Medicine_docx/12512039
命令行下载
curl -L -o "Table_1_Genomics of Peripheral T-Cell Lymphoma and Its Implications for Personalized Medicine.docx" "https://ndownloader.figshare.com/files/23220479"
文件清单
Table_1_Genomics of Peripheral T-Cell Lymphoma and Its Implications for Personalized Medicine.docx（712.31 KB）
文件总体积 712.31 KB（源站 API 实测）。
数据说明
Peripheral T-cell lymphoma (PTCL) is a rare, heterogenous group of mature T-cell neoplasms that comprise 10–15% of non-Hodgkin lymphoma cases in the United States. All subtypes of PTCL, except for ALK+ anaplastic T-cell lymphoma, are associated with poor prognosis, with median overall survival (OS) rates of 1–3 years. The diagnosis of PTCL is mainly based on clinical presentation, morphologic features, and immunophenotypes. Recent advances in genome sequencing and gene expression profiling have given new insights into the pathogenesis and molecular biology of PTCL. An enhanced understanding of its genomic landscape holds the promise of refining the diagnosis, prognosis, and management of PTCL. In this review, we examine recently discovered genetic abnormalities identified by molecular profiling in 3 of the most common types of PTCL: RHOAG17V and epigenetic regulator mutations in angioimmunoblastic T-cell lymphoma, ALK expression and JAK/STAT3 pathway mutations in anaplastic T-cell lymphoma, and T-follicular helper phenotype and GATA3/TBX21 expression in PTCL-not otherwise specified. We also discuss the implications of these abnormalities for clinical practice, new/potential targeted therapies, and the role of personalized medicine in the management of PTCL.
许可
CC BY 4.0
引用
学术使用请引用 DOI 10.3389/fonc.2020.00898.s001（source: https://frontiersin.figshare.com/articles/dataset/Table_1_Genomics_of_Peripheral_T-Cell_Lymphoma_and_Its_Implications_for_Personalized_Medicine_docx/12512039）。
数据缺失？
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