MYCN依赖性髓母细胞瘤癌症传播细胞的分子与体内特征研究数据集

资源简介

MYCN依赖性髓母细胞瘤癌症传播细胞的分子与体内特征研究数据集

【数据集背景】

本数据集源站标题为《Molecular and In Vivo Characterization of Cancer-Propagating Cells Derived from MYCN-Dependent Medulloblastoma》。配套论文《Molecular and In Vivo Characterization of Cancer-Propagating Cells Derived from MYCN-Dependent Medulloblastoma》发表于 PLOS ONE（2015），DOI：10.1371/journal.pone.0119834。源站首次发布：2015-03-18。

【数据内容】

源站原始描述：Medulloblastoma (MB) is the most common malignant pediatric brain tumor. While the pathways that are deregulated in MB remain to be fully characterized, amplification and/or overexpression of the MYCN gene, which is has a critical role in cerebellar development as a regulator of neural progenitor cell fate, has been identified in several MB subgroups. Phenotypically, aberrant expression of MYCN is associated with the large-cell/anaplastic MB variant, which accounts for 5-15% of cases and is asso…

【数据结构与技术规格】

文件数 14 个，合计 36.34 MB。S1_Fig.tif：image/tiff，4.66 MB。数据集 DOI：10.1371/journal.pone.0119834。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：progenitor cell fate、cell RNA assay data、mycn、mln、GTML neurospheres、GTML MB allografts、role。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Molecular_and_In_Vivo_Characterization_of_Cancer_Propagating_Cells_Derived_from_MYCN_Dependent_Medulloblastoma/1341745

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Ahmad, Zai; Jasnos, Lukasz; Gil, Veronica; Howell, Louise; Hallsworth, Albert; Petrie, Kevin; et al. (2016). Molecular and In Vivo Characterization of Cancer-Propagating Cells Derived from MYCN-Dependent Medulloblastoma. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-30，引用时请注意版本时效。