肿瘤患者同轴系统引导活检诊断准确性与安全性数据表1

数据集获取（Figshare）

• 源站标题：Data_Sheet_1_Diagnostic Accuracy and Safety of Coaxial System in Oncology Patients Treated in a Specialist Cancer Center With Prospective Validation Within Clinical Trial Data.docx
• DOI：10.3389/fonc.2020.01634.s001
• 发布日期：2020-09-04
• 文件数：1 个
• 文件总体积：38.44 KB
• 源站页面：https://frontiersin.figshare.com/articles/dataset/Data_Sheet_1_Diagnostic_Accuracy_and_Safety_of_Coaxial_System_in_Oncology_Patients_Treated_in_a_Specialist_Cancer_Center_With_Prospective_Validation_Within_Clinical_Trial_Data_docx/12919253

命令行下载

curl -L -o "Data_Sheet_1_Diagnostic Accuracy and Safety of Coaxial System in Oncology Patients Treated in a Specialist Cancer Center With Prospective Validation W.docx" "https://ndownloader.figshare.com/files/24578891"

文件清单

• Data_Sheet_1_Diagnostic Accuracy and Safety of Coaxial System in Oncology Patients Treated in a Specialist Cancer Center With Prospective Validation W.docx（38.44 KB）

文件总体积 38.44 KB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

BackgroundImage-guided tissue biopsies are critically important in the diagnosis and management of cancer patients. High-yield samples are also vital for biomarker and resistance mechanism discovery through molecular/genomic analyses.
Patients and MethodsAll consecutive patients who underwent plugged image-guided biopsy at Royal Marsden from June 2013 until September 2016 were included in the analysis. In the next step, a second cohort of patients prospectively treated within two clinical trials (PROSPECT-C and PROSPECT-R) were assessed for the DNA yield from biopsies assessed for complex genomic analysis.
ResultsA total of 522 plugged core biopsies were performed in 457 patients [men, 52%; median age, 63 years (range, 17–93)]. Histological diagnosis was achieved in 501 of 522 (96%) performed biopsies. Age, gender, modality, metastatic site, and seniority of the interventionist were not found to be significant factors associated with odds of failure on a logistic regression. Seventeen (3.3%) were admitted due to biopsy-related complications; nine, three, two, one, one, and one were admitted for grade I/II pain control, sepsis, vasovagal syncope, thrombosis, hematuria, and deranged liver functions, respectively; two patients with right upper quadrant pain after liver biopsy were found to have radiologically confirmed subcapsular hematoma requiring conservative treatment. One patient (0.2%) developed grade III hemorrhage following biopsy of a gastric gastrointestinal stromal tumor (GIST). Overall molecular analysis was successful in 89% (197/222 biopsies). Prospective validation in 62 biopsies gave success rates of 92.06 and 79.03% for DNA extraction of >1 μm and tmour content of >20%, respectively.
ConclusionThe probability of diagnostic success for complex molecular analysis is increased with plugged large coaxial needle biopsy technique, which also minimizes complications and reduces hospital stay. High-yield DNA acquisition allows genomic molecular characterization for personalized medicine.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.3389/fonc.2020.01634.s001（source: https://frontiersin.figshare.com/articles/dataset/Data_Sheet_1_Diagnostic_Accuracy_and_Safety_of_Coaxial_System_in_Oncology_Patients_Treated_in_a_Specialist_Cancer_Center_With_Prospective_Validation_Within_Clinical_Trial_Data_docx/12919253）。