癌症患者体重分布数据集
包含13,036名癌症患者的体重和体表面积数据，用于分析分布及影响因素，辅助药物剂量确定。
基本信息
资源简介
癌症患者体重分布数据集
【数据集背景】
本数据集源站标题为《Cancer patients’ BW distribution.》。源站首次发布：2024-12-17。
【数据内容】
源站原始描述：Although body weight (BW) and body surface area (BSA) are utilized to establish the appropriate dosage of anticancer drugs, their distribution in cancer patients is poorly studied, making it challenging to predict the amount of drug use and related costs of BW or BAS-dosed regimens. This study investigates the distribution of BW and BSA in adults with selected cancers who initiated systemic anticancer treatment in the eastern Emilia-Romagna region hospitals between 2011 and 2021. BW and BSA were…
【数据结构与技术规格】
文件数 1 个，合计 9.73 KB。Table 1.xls：application/vnd.ms-excel，9.73 KB。数据集 DOI：10.1371/journal.pone.0314452.t001。
【主题与分类】
源站学科分类：Medicine、Pharmacology、Environmental Sciences not elsewhere classified、Biological Sciences not elsewhere classified、Cancer。主题标签：romagna region hospitals、assist regulatory bodies、analysis included 20、body surface area、new treatment line、new chemotherapy drugs、634 treatment lines、th </ sup、linear regression model、2 </ sup。
【适用方向】
结构化表格数据可直接用于统计建模、特征工程与队列分析。
【获取与许可】
源站页面：https://plos.figshare.com/articles/dataset/Cancer_patients_BW_distribution_/28047720
使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。
规范引用：Danesi, Valentina; Andalò, Alice; Cavallucci, Martina; Balzi, William; Gentili, Nicola; Altini, Mattia; et al. (2024). Cancer patients’ BW distribution.. PLOS ONE. Dataset
下载信息
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使用方式
数据集获取（Figshare）
- 源站标题：Cancer patients’ BW distribution.
- DOI：10.1371/journal.pone.0314452.t001
- 发布日期：2024-12-17
- 文件数：1 个
- 文件总体积：9.73 KB
- 源站页面：https://plos.figshare.com/articles/dataset/Cancer_patients_BW_distribution_/28047720
命令行下载
curl -L -o "Table 1.xls" "https://ndownloader.figshare.com/files/51254061"
文件清单
Table 1.xls（9.73 KB）
文件总体积 9.73 KB（源站 API 实测）。
数据说明
Although body weight (BW) and body surface area (BSA) are utilized to establish the appropriate dosage of anticancer drugs, their distribution in cancer patients is poorly studied, making it challenging to predict the amount of drug use and related costs of BW or BAS-dosed regimens. This study investigates the distribution of BW and BSA in adults with selected cancers who initiated systemic anticancer treatment in the eastern Emilia-Romagna region hospitals between 2011 and 2021. BW and BSA were collected at the first cycle of each new treatment line, with multiple measurements for patients receiving various treatments or treating for other primary malignancies. Results were grouped by sex, tumor site and treatment setting, and the normal distribution hypothesis was tested for each group. Both linear regression model and quantile regression at the 50th, 25th and 75th percentiles were run to explore the factors influencing BSA. The analysis included 20,634 treatment lines and the corresponding BW and BSA measures from a sample of 13,036 patients. The average BW was 68.05kg (64.20kg for females and 75.07kg for males) and the average BSA was 1.76m2 (1.66m2 for females and 1.87m2 for males). In women, the highest BW was in breast and colon groups, while in men, it was associated with prostate and rectum cancers. The model indicated significant association between BSA, age, sex and tumor localization. Notably, stomach and lung cancers were linked to lower BSA for both sexes (for females -0.081 and -0.041m2 respectively compared to those with breast cancer). Advanced settings were related to lower BSA than neoadjuvant treatment, especially for stomach cancer patients, who experienced a weight loss of 3 to 6kg as therapy progressed. The regression models for predicting BSA can assist regulatory bodies in determining reimbursement for new chemotherapy drugs and help hospitals forecast drug utilization and expenditure more accurately.
许可
CC BY 4.0
引用
学术使用请引用 DOI 10.1371/journal.pone.0314452.t001（source: https://plos.figshare.com/articles/dataset/Cancer_patients_BW_distribution_/28047720）。
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