阿霉素治疗加速乳腺癌骨转移临床前模型骨丢失数据集

资源简介

阿霉素治疗加速乳腺癌骨转移临床前模型骨丢失数据集

【数据集背景】

本数据集源站标题为《Doxorubicin treatment accelerates bone loss in preclinical breast cancer bone metastasis model.》。配套论文《Doxorubicin-Mediated Bone Loss in Breast Cancer Bone Metastases Is Driven by an Interplay between Oxidative Stress and Induction of TGFβ》发表于 PLoS ONE（2013），DOI：10.1371/journal.pone.0078043。源站首次发布：2013-10-30。

【数据内容】

源站原始描述：Five-week old female Balb/C mice received either 5 mg/Kg doxorubicin (i.p. once weekly for three weeks) or PBS and microCT of tibiae were performed. For orthotopic breast cancer bone metastasis model, another set of four-week old female Balb/C mice were injected in the left #4 mammary fat pad using a bone-tropic 4T1 cell line and upon tumor development (palpable size after 1 week) mice were treated with either PBS or doxorubicin (5 mg/Kg doxorubicin, i.p., once weekly for three weeks) and microC…

【数据结构与技术规格】

文件数 1 个，合计 5.22 MB。Figure 1.tif：image/tiff，5.22 MB。数据集 DOI：10.1371/journal.pone.0078043.g001。

【主题与分类】

源站学科分类：Medicine、Cell Biology、Genetics、Physiology、Environmental Sciences not elsewhere classified、Ecology。主题标签：NAC、trabecular bone volume、BV、TGF β、breast cancer bone metastasis model、osteolytic bone damage、antibody、osteolytic lesion areas、SOD、doxorubicin treatment increases。

【适用方向】

源站学科分类标注为 Medicine、Cell Biology、Genetics、Physiology、Environmental Sciences not elsewhere classified、Ecology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Doxorubicin_treatment_accelerates_bone_loss_in_preclinical_breast_cancer_bone_metastasis_model_/837183

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Rana, Tapasi; Chakrabarti, Anwesa; Freeman, Michael; Biswas, Swati (2016). Doxorubicin treatment accelerates bone loss in preclinical breast cancer bone metastasis model.. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-03，引用时请注意版本时效。