启动免疫球蛋白替代疗法有助于减少美国先天性免疫缺陷患者的严重感染并将医疗资源利用转向门诊服务

数据集获取（Figshare）

• 源站标题：Initiating immunoglobulin replacement therapy helps reduce severe infections and shifts healthcare resource utilization to outpatient services among US patients with inborn errors of immunity
• DOI：10.6084/m9.figshare.26049805.v3
• 发布日期：2024-08-13
• 文件数：8 个
• 文件总体积：3.31 MB
• 源站页面：https://tandf.figshare.com/articles/dataset/Initiating_immunoglobulin_replacement_therapy_helps_reduce_severe_infections_and_shifts_healthcare_resource_utilization_to_outpatient_services_among_US_patients_with_inborn_errors_of_immunity/26049805

命令行下载

curl -L -o "ijme_a_2368987_sm1178.eps" "https://ndownloader.figshare.com/files/48403705"
curl -L -o "ijme_a_2368987_sm1172.eps" "https://ndownloader.figshare.com/files/48403708"
curl -L -o "ijme_a_2368987_sm1158.jpg" "https://ndownloader.figshare.com/files/48403714"
curl -L -o "ijme_a_2368987_sm1157.jpg" "https://ndownloader.figshare.com/files/48403717"
curl -L -o "ijme_a_2368987_sm1146.eps" "https://ndownloader.figshare.com/files/48403723"
curl -L -o "ijme_a_2368987_sm1145.eps" "https://ndownloader.figshare.com/files/48403726"
curl -L -o "ijme_a_2368987_sm1144.eps" "https://ndownloader.figshare.com/files/48403729"
curl -L -o "ijme_a_2368987_sm1065.docx" "https://ndownloader.figshare.com/files/48403732"

文件清单

• ijme_a_2368987_sm1178.eps（770.15 KB）
• ijme_a_2368987_sm1172.eps（795.43 KB）
• ijme_a_2368987_sm1158.jpg（123.25 KB）
• ijme_a_2368987_sm1157.jpg（99.36 KB）
• ijme_a_2368987_sm1146.eps（485.37 KB）
• ijme_a_2368987_sm1145.eps（377.93 KB）
• ijme_a_2368987_sm1144.eps（588.36 KB）
• ijme_a_2368987_sm1065.docx（73.81 KB）

文件总体积 3.31 MB（源站 API 实测）。

数据加载示例（图像类）

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Patients with inborn errors of immunity (IEI) are predisposed to severe recurrent/chronic infections, and often require hospitalization, resulting in substantial burden to patients/healthcare systems. While immunoglobulin replacement therapies (IgRTs) are the standard first-line treatment for most forms of IEI, limited real-world data exist regarding clinical characteristics and treatment costs for patients with IEI initiating such treatment. This retrospective analysis examined infection and treatment characteristics in US patients with IEI initiating IgRT with immune globulin infusion (human), 10% (IG10%). Healthcare resource utilization (HCRU) and associated costs before and after treatment initiation were compared. Additionally, the impact of COVID-19 on infection diagnoses was evaluated.
Patients with IEI initiating IG10% between July 2012 and August 2019 were selected from Merative MarketScan Databases using diagnosis/prescription codes. Patients were followed 6 months before and after first IG10% claim date. Demographic and clinical characteristics were described. Treatment characteristics and HCRU before and after IG10% initiation were compared. Infection diagnoses during 2020 and 2019 (March–December) were compared.
The study included 1,497 patients with IEI diagnoses (mean age = 43.4 years) initiating IG10%, with frequently reported comorbidities like asthma (32.1%). Following IG10% initiation, fewer severe infection diagnoses (11.6% vs 19.9%), fewer infection-related inpatient (10.8% vs 19.5%) and outpatient services (71.6% vs 79.9%), and lower infection-related total healthcare costs ($7,849 vs $13,995; p Patients with IEI are susceptible to severe infections leading to high disease burden and treatment costs. Following IG10% initiation, we observed fewer infections, lower infection-related treatment costs, and shift in care (inpatient to outpatient) leading to significant cost savings. Among patients with IEI, 27% fewer infection diagnoses were observed during the early COVID-19 lockdown period than the prior year.
Some people are born with inborn errors of immunity, or IEI. This study included 1,497 people with IEI who recently started taking a

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.6084/m9.figshare.26049805.v3（source: https://tandf.figshare.com/articles/dataset/Initiating_immunoglobulin_replacement_therapy_helps_reduce_severe_infections_and_shifts_healthcare_resource_utilization_to_outpatient_services_among_US_patients_with_inborn_errors_of_immunity/26049805）。