PAK抑制剂IPA-3诱导人造血细胞死亡及影响细胞对纤连蛋白粘附性的数据集

资源简介

PAK抑制剂IPA-3诱导人造血细胞死亡及影响细胞对纤连蛋白粘附性的数据集

【数据集背景】

本数据集源站标题为《Group I PAK Inhibitor IPA-3 Induces Cell Death and Affects Cell Adhesivity to Fibronectin in Human Hematopoietic Cells》。配套论文《Group I PAK Inhibitor IPA-3 Induces Cell Death and Affects Cell Adhesivity to Fibronectin in Human Hematopoietic Cells》发表于 PLoS ONE（2014），DOI：10.1371/journal.pone.0092560。源站首次发布：2014-03-24。

【数据内容】

源站原始描述：P21-activated kinases (PAKs) are involved in the regulation of multiple processes including cell proliferation, adhesion and migration. However, the current knowledge about their function is mainly based on results obtained in adherent cell types. We investigated the effect of group I PAK inhibition using the compound IPA-3 in a variety of human leukemic cell lines (JURL-MK1, MOLM-7, K562, CML-T1, HL-60, Karpas-299, Jurkat, HEL) as well as in primary blood cells. IPA-3 induced cell death with EC…

【数据结构与技术规格】

文件数 8 个，合计 16.88 MB。Figure_S1.tif：image/tiff，414.54 KB。Figure_S2.tif：image/tiff，3.58 MB。Figure_S3.tif：image/tiff，892.53 KB。数据集 DOI：10.1371/journal.pone.0092560。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：Biochemistry、proteins、cell biology、Cell motility、cell migration、Cell processes、Cell death、Cell growth、Cellular structures and organelles、Extracellular matrix。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Group_I_PAK_Inhibitor_IPA_3_Induces_Cell_Death_and_Affects_Cell_Adhesivity_to_Fibronectin_in_Human_Hematopoietic_Cells_/972519

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Kuželová, Kateřina; Grebeňová, Dana; Holoubek, Aleš; Röselová, Pavla; Obr, Adam (2016). Group I PAK Inhibitor IPA-3 Induces Cell Death and Affects Cell Adhesivity to Fibronectin in Human Hematopoietic Cells. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。