慢性淋巴细胞白血病易感性变异的后GWAS功能表征

资源简介

慢性淋巴细胞白血病易感性变异的后GWAS功能表征

【数据集背景】

本数据集源站标题为《Post-GWAS Functional Characterization of Susceptibility Variants for Chronic Lymphocytic Leukemia》。配套论文《Post-GWAS Functional Characterization of Susceptibility Variants for Chronic Lymphocytic Leukemia》发表于 PLoS ONE（2012），DOI：10.1371/journal.pone.0029632。源站首次发布：2012-01-03。

【数据内容】

源站原始描述：Recent genome-wide association studies (GWAS) have identified several gene variants associated with sporadic chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). Many of these CLL/SLL susceptibility loci are located in non-coding or intergenic regions, posing a significant challenge to determine their potential functional relevance. Here, we review the literature of all CLL/SLL GWAS and validation studies, and apply eQTL analysis to identify putatively functional SNPs that affect g…

【数据结构与技术规格】

文件数 2 个，合计 280.16 KB。Table_S1.xlsx：application/vnd.openxmlformats-officedocument.spreadsheetml.sheet，132.55 KB。Table_S2.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，147.61 KB。数据集 DOI：10.1371/journal.pone.0029632。

【主题与分类】

源站学科分类：Cancer、Biological Sciences、Genetics。主题标签：post-gwas、characterization、susceptibility、variants、lymphocytic、leukemia。

【适用方向】

源站学科分类标注为 Cancer、Biological Sciences、Genetics。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Post_GWAS_Functional_Characterization_of_Susceptibility_Variants_for_Chronic_Lymphocytic_Leukemia/129993

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：C. M. Sillé, Fenna; Thomas, Reuben; Smith, Martyn T.; Conde, Lucia; F. Skibola, Christine (2016). Post-GWAS Functional Characterization of Susceptibility Variants for Chronic Lymphocytic Leukemia. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-04，引用时请注意版本时效。