胎儿酒精暴露通过表观遗传机制降低多巴胺受体D2并增加垂体重量和催乳素产生

资源简介

胎儿酒精暴露通过表观遗传机制降低多巴胺受体D2并增加垂体重量和催乳素产生

【数据集背景】

本数据集源站标题为《Fetal Alcohol Exposure Reduces Dopamine Receptor D2 and Increases Pituitary Weight and Prolactin Production via Epigenetic Mechanisms》。配套论文《Fetal Alcohol Exposure Reduces Dopamine Receptor D2 and Increases Pituitary Weight and Prolactin Production via Epigenetic Mechanisms》发表于 PLOS ONE（2015），DOI：10.1371/journal.pone.0140699。源站首次发布：2015-10-28。

【数据内容】

源站原始描述：Recent evidence indicated that alcohol exposure during the fetal period increases the susceptibility to tumor development in mammary and prostate tissues. Whether fetal alcohol exposure increases the susceptibility to prolactin-producing tumor (prolactinoma) development in the pituitary was studied by employing the animal model of estradiol-induced prolactinomas in Fischer 344 female rats. We employed an animal model of fetal alcohol exposure that simulates binge alcohol drinking during the firs…

【数据结构与技术规格】

文件数 2 个，合计 2.04 MB。S1_Fig.pdf：application/pdf，1.53 MB。S2_Fig.pdf：application/pdf，513.54 KB。数据集 DOI：10.1371/journal.pone.0140699。

【主题与分类】

源站学科分类：Uncategorised。主题标签：rat chow diet、alcohol exposure programs、Increases Pituitary Weight、Prolactinoma、susceptibility、D 2R promoter methylation、binge alcohol drinking、plasma PRL levels、Fetal alcohol exposure、D 2R gene promoter。

【适用方向】

源站学科分类标注为 Uncategorised。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Fetal_Alcohol_Exposure_Reduces_Dopamine_Receptor_D2_and_Increases_Pituitary_Weight_and_Prolactin_Production_via_Epigenetic_Mechanisms_/1587596

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Gangisetty, Omkaram; Wynne, Olivia; Jabbar, Shaima; Nasello, Cara; K. Sarkar, Dipak (2016). Fetal Alcohol Exposure Reduces Dopamine Receptor D2 and Increases Pituitary Weight and Prolactin Production via Epigenetic Mechanisms. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-03，引用时请注意版本时效。