抑制前列腺素转运蛋白PGT降低高血压大鼠和小鼠血压

资源简介

抑制前列腺素转运蛋白PGT降低高血压大鼠和小鼠血压

【数据集背景】

本数据集源站标题为《Inhibition of the Prostaglandin Transporter PGT Lowers Blood Pressure in Hypertensive Rats and Mice》。配套论文《Inhibition of the Prostaglandin Transporter PGT Lowers Blood Pressure in Hypertensive Rats and Mice》发表于 PLOS ONE（2015），DOI：10.1371/journal.pone.0131735。源站首次发布：2015-06-29。

【数据内容】

源站原始描述：Inhibiting the synthesis of endogenous prostaglandins with nonsteroidal anti-inflammatory drugs exacerbates arterial hypertension. We hypothesized that the converse, i.e., raising the level of endogenous prostaglandins, might have anti-hypertensive effects. To accomplish this, we focused on inhibiting the prostaglandin transporter PGT (SLCO2A1), which is the obligatory first step in the inactivation of several common PGs. We first examined the role of PGT in controlling arterial blood pressure b…

【数据结构与技术规格】

文件数 4 个，合计 13.56 MB。S1_Fig.pdf：application/pdf，53.58 KB。S2_Fig.pdf：application/pdf，372.80 KB。数据集 DOI：10.1371/journal.pone.0131735。

【主题与分类】

源站学科分类：Uncategorised。主题标签：prostaglandin transporter PGT、PGE 2、T 26A、2a、blood pressure blood pressure、PGE 2 T 26A、SLCO、Prostaglandin Transporter PGT Lowers Blood Pressure、blood pressure、exogenous PGE 2.。

【适用方向】

源站学科分类标注为 Uncategorised。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Inhibition_of_the_Prostaglandin_Transporter_PGT_Lowers_Blood_Pressure_in_Hypertensive_Rats_and_Mice_/1468231

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Chi, Yuling; Jasmin, Jean-Francois; Seki, Yoshinori; P. Lisanti, Michael; J. Charron, Maureen; Lefer, David J.; et al. (2016). Inhibition of the Prostaglandin Transporter PGT Lowers Blood Pressure in Hypertensive Rats and Mice. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-30，引用时请注意版本时效。