巴德特-别德尔综合征基因BBS9/PTHB1敲低导致纤毛缺陷

资源简介

巴德特-别德尔综合征基因BBS9/PTHB1敲低导致纤毛缺陷

【数据集背景】

本数据集源站标题为《Knockdown of Bardet-Biedl Syndrome Gene BBS9/PTHB1 Leads to Cilia Defects》。配套论文《Knockdown of Bardet-Biedl Syndrome Gene BBS9/PTHB1 Leads to Cilia Defects》发表于 PLoS ONE（2012），DOI：10.1371/journal.pone.0034389。源站首次发布：2012-03-29。

【数据内容】

源站原始描述：Bardet-Biedl Syndrome (BBS, MIM#209900) is a genetically heterogeneous disorder with pleiotropic phenotypes that include retinopathy, mental retardation, obesity and renal abnormalities. Of the 15 genes identified so far, seven encode core proteins that form a stable complex called BBSome, which is implicated in trafficking of proteins to cilia. Though BBS9 (also known as PTHB1) is reportedly a component of BBSome, its direct function has not yet been elucidated. Using zebrafish as a model, we s…

【数据结构与技术规格】

文件数 2 个，合计 1.70 MB。Figure_S1.tif：image/tiff，1.47 MB。Figure_S2.tif：image/tiff，230.74 KB。数据集 DOI：10.1371/journal.pone.0034389。

【主题与分类】

源站学科分类：Neuroscience、Hematology、Medicine、Developmental Biology、Genetics。主题标签：knockdown、bardet-biedl、leads、cilia、defects。

【适用方向】

源站学科分类标注为 Neuroscience、Hematology、Medicine、Developmental Biology、Genetics。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Knockdown_of_Bardet_Biedl_Syndrome_Gene_BBS9_PTHB1_Leads_to_Cilia_Defects/127017

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Veleri, Shobi; Bishop, Kevin; E. Dalle Nogare, Damian; A. English, Milton; J. Foskett, Trevor; Chitnis, Ajay; et al. (2016). Knockdown of Bardet-Biedl Syndrome Gene BBS9/PTHB1 Leads to Cilia Defects. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。