高活性神经内分泌分泌导致线虫巴德特-别德尔综合征突变体的大小、摄食和代谢缺陷

资源简介

高活性神经内分泌分泌导致线虫巴德特-别德尔综合征突变体的大小、摄食和代谢缺陷

【数据集背景】

本数据集源站标题为《Hyperactive Neuroendocrine Secretion Causes Size, Feeding, and Metabolic Defects of C. elegans Bardet-Biedl Syndrome Mutants》。配套论文《Hyperactive Neuroendocrine Secretion Causes Size, Feeding, and Metabolic Defects of C. elegans Bardet-Biedl Syndrome Mutants》发表于 PLoS Biology（2011），DOI：10.1371/journal.pbio.1001219。源站首次发布：2011-12-13。

【数据内容】

源站原始描述：Bardet-Biedl syndrome, BBS, is a rare autosomal recessive disorder with clinical presentations including polydactyly, retinopathy, hyperphagia, obesity, short stature, cognitive impairment, and developmental delays. Disruptions of BBS proteins in a variety of organisms impair cilia formation and function and the multi-organ defects of BBS have been attributed to deficiencies in various cilia-associated signaling pathways. In C. elegans, bbs genes are expressed exclusively in the sixty ciliated s…

【数据结构与技术规格】

文件数 6 个，合计 62.53 MB。数据集 DOI：10.1371/journal.pbio.1001219。

【主题与分类】

源站学科分类：Neuroscience、Genetics。主题标签：hyperactive、neuroendocrine、secretion、causes、metabolic、defects、bardet-biedl、mutants。

【适用方向】

源站学科分类标注为 Neuroscience、Genetics。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Hyperactive_Neuroendocrine_Secretion_Causes_Size_Feeding_and_Metabolic_Defects_of_C_elegans_Bardet_Biedl_Syndrome_Mutants/130759

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：H. Lee, Brian; Liu, Jason; Wong, Daisy; Srinivasan, Supriya; Ashrafi, Kaveh (2016). Hyperactive Neuroendocrine Secretion Causes Size, Feeding, and Metabolic Defects of C. elegans Bardet-Biedl Syndrome Mutants. PLOS Biology. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。