一种新型饮食诱导的伴有纤维化的脂肪性肝炎小鼠模型数据集，用于非酒精性脂肪性肝炎候选药物的筛选与评估

资源简介

一种新型饮食诱导的伴有纤维化的脂肪性肝炎小鼠模型数据集，用于非酒精性脂肪性肝炎候选药物的筛选与评估

【数据集背景】

本数据集源站标题为《Dataset for: A novel diet-induced murine model of steatohepatitis with fibrosis for screening and evaluation of drug candidates for non-alcoholic steatohepatitis》。配套论文《A novel diet‐induced murine model of steatohepatitis with fibrosis for screening and evaluation of drug candidates for nonalcoholic steatohepatitis》发表于 Physiological Reports（2016），DOI：10.14814/phy2.13016。源站首次发布：2017-03-29。

【数据内容】

源站原始描述：Many animal models of non-alcoholic steatohepatitis have been reported. While these models exhibit mild onset of hepatitis and fibrosis, induction is often slow. For faster screening of drug candidates, there is a compelling need for convenient animal models of steatohepatitis and non-alcoholic steatohepatitis in which fatty liver and hepatitis are stably induced within a short period. Here, we analyzed the hepatic lipid composition in non-alcoholic steatohepatitis, and used this information to…

【数据结构与技术规格】

文件数 1 个，合计 36.71 KB。CHIEK_1_2_Supp Table 1_Sept 22.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，36.71 KB。数据集 DOI：10.6084/m9.figshare.3984502.v1。

【主题与分类】

源站学科分类：Animal physiology - biophysics、Animal physiology - cell、Animal physiology - systems、Systems biology。主题标签：animal model、screening、Non-alcoholic steatohepatitis、branched-chain amino acids、Physiology、Systems Biology。

【适用方向】

源站学科分类标注为 Animal physiology - biophysics、Animal physiology - cell、Animal physiology - systems、Systems biology。

【获取与许可】

源站页面：https://wiley.figshare.com/articles/dataset/Dataset_for_A_novel_diet-induced_murine_model_of_steatohepatitis_with_fibrosis_for_screening_and_evaluation_of_drug_candidates_for_non-alcoholic_steatohepatitis/3984502

使用许可：CC0（https://creativecommons.org/publicdomain/zero/1.0/）。

规范引用：Ejima, Chieko; Kuroda, Haruna; Ishizaki, Sonoko (2017). Dataset for: A novel diet-induced murine model of steatohepatitis with fibrosis for screening and evaluation of drug candidates for non-alcoholic steatohepatitis. Wiley. Dataset

【使用注意】

· 源站最后修改于 2023-06-02，引用时请注意版本时效。