葡萄糖刺激诱导INS-1E胰岛素瘤细胞系中线粒体形态动态变化以促进胰岛素分泌

资源简介

葡萄糖刺激诱导INS-1E胰岛素瘤细胞系中线粒体形态动态变化以促进胰岛素分泌

【数据集背景】

本数据集源站标题为《Glucose Stimulation Induces Dynamic Change of Mitochondrial Morphology to Promote Insulin Secretion in the Insulinoma Cell Line INS-1E》。配套论文《Glucose Stimulation Induces Dynamic Change of Mitochondrial Morphology to Promote Insulin Secretion in the Insulinoma Cell Line INS-1E》发表于 PLoS ONE（2013），DOI：10.1371/journal.pone.0060810。源站首次发布：2013-04-03。

【数据内容】

源站原始描述：Fission and fusion of mitochondrial tubules are the major processes regulating mitochondrial morphology. However, the physiological significance of mitochondrial shape change is poorly understood. Glucose-stimulated insulin secretion (GSIS) in pancreatic β-cells requires mitochondrial ATP production which evokes Ca2+ influx through plasma membrane depolarization, triggering insulin vesicle exocytosis. Therefore, GSIS reflects mitochondrial function and can be used for evaluating functional chang…

【数据结构与技术规格】

文件数 8 个，合计 8.40 MB。Figure_S1.tif：image/tiff，360.61 KB。Figure_S2.tif：image/tiff，959.87 KB。Figure_S3.tif：image/tiff，814.84 KB。数据集 DOI：10.1371/journal.pone.0060810。

【主题与分类】

源站学科分类：Physiology、Biochemistry、Chemistry、Cell Biology。主题标签：stimulation、mitochondrial、morphology、insulin、secretion、insulinoma。

【适用方向】

源站学科分类标注为 Physiology、Biochemistry、Chemistry、Cell Biology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Glucose_Stimulation_Induces_Dynamic_Change_of_Mitochondrial_Morphology_to_Promote_Insulin_Secretion_in_the_Insulinoma_Cell_Line_INS_1E_/664581

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Sook Jhun, Bong; Lee, Hakjoo; Jin, Zheng-Gen; Yoon, Yisang (2016). Glucose Stimulation Induces Dynamic Change of Mitochondrial Morphology to Promote Insulin Secretion in the Insulinoma Cell Line INS-1E. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。