组织型纤溶酶原激活剂在动脉导管重塑中的作用

资源简介

组织型纤溶酶原激活剂在动脉导管重塑中的作用

【数据集背景】

本数据集源站标题为《Tissue-type plasminogen activator contributes to remodeling of the rat ductus arteriosus》。配套论文《Tissue-type plasminogen activator contributes to remodeling of the rat ductus arteriosus》发表于 PLOS ONE（2018），DOI：10.1371/journal.pone.0190871。源站首次发布：2018-01-05。

【数据内容】

源站原始描述：Aims The ductus arteriosus (DA) closes after birth to adapt to the robust changes in hemodynamics, which require intimal thickening (IT) to occur. The smooth muscle cells of the DA have been reported to play important roles in IT formation. However, the roles of the endothelial cells (ECs) have not been fully investigated. We herein focused on tissue-type plasminogen activator (t-PA), which is a DA EC dominant gene, and investigated its contribution to IT formation in the DA. Methods and results…

【数据结构与技术规格】

文件数 4 个，合计 7.20 MB。S1 Fig.tif：image/tiff，2.73 MB。S2 Fig.tif：image/tiff，678.78 KB。S3 Fig.tif：image/tiff，3.78 MB。数据集 DOI：10.1371/journal.pone.0190871。

【主题与分类】

源站学科分类：Biochemistry、Cell Biology、Molecular Biology、Pharmacology、Biotechnology、Developmental Biology。主题标签：full-term rat fetuses、RT-PCR、EC-mediated plasminogen-plasmin conversion、rat DA ECs、gelatinase activity、t-PA protein expression、Tissue-type plasminogen activator、pre-term rat fetuses、IEL disruption、rat ductus arteriosus。

【适用方向】

源站学科分类标注为 Biochemistry、Cell Biology、Molecular Biology、Pharmacology、Biotechnology、Developmental Biology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Tissue-type_plasminogen_activator_contributes_to_remodeling_of_the_rat_ductus_arteriosus/5763882

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Saito, Junichi; Yokoyama, Utako; Nicho, Naoki; Zheng, Yun-Wen; Ichikawa, Yasuhiro; Ito, Satoko; et al. (2018). Tissue-type plasminogen activator contributes to remodeling of the rat ductus arteriosus. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。