补体因子B激活对小鼠和人类心肌缺血再灌注损伤的贡献

资源简介

补体因子B激活对小鼠和人类心肌缺血再灌注损伤的贡献

【数据集背景】

本数据集源站标题为《Activation of complement factor B contributes to murine and human myocardial ischemia/reperfusion injury》。配套论文《Activation of complement factor B contributes to murine and human myocardial ischemia/reperfusion injury》发表于 PLOS ONE（2017），DOI：10.1371/journal.pone.0179450。源站首次发布：2017-06-29。

【数据内容】

源站原始描述：The pathophysiology of myocardial injury that results from cardiac ischemia and reperfusion (I/R) is incompletely understood. Experimental evidence from murine models indicates that innate immune mechanisms including complement activation via the classical and lectin pathways are crucial. Whether factor B (fB), a component of the alternative complement pathway required for amplification of complement cascade activation, participates in the pathophysiology of myocardial I/R injury has not been ad…

【数据结构与技术规格】

文件数 5 个，合计 5.69 MB。S1 Fig.eps：application/postscript，985.53 KB。S2 Fig.eps：application/postscript，1.53 MB。S3 Fig.eps：application/postscript，1.80 MB。数据集 DOI：10.1371/journal.pone.0179450。

【主题与分类】

源站学科分类：Biochemistry、Medicine、Cell Biology、Genetics、Molecular Biology、Biotechnology。主题标签：heart ischemia、murine models、complement activation、complement factor B、intracoronary blood samples、pathophysiological amplifier、Experimental evidence、lectin pathways、WT serum、blood levels。

【适用方向】

源站学科分类标注为 Biochemistry、Medicine、Cell Biology、Genetics、Molecular Biology、Biotechnology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Activation_of_complement_factor_B_contributes_to_murine_and_human_myocardial_ischemia_reperfusion_injury/5156749

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Chun, Nicholas; Haddadin, Ala S.; Liu, Junying; Hou, Yunfang; Wong, Karen A.; Lee, Daniel; et al. (2017). Activation of complement factor B contributes to murine and human myocardial ischemia/reperfusion injury. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。