遗传性出血性毛细血管扩张症中的长链非编码RNA表达谱

资源简介

遗传性出血性毛细血管扩张症中的长链非编码RNA表达谱

【数据集背景】

本数据集源站标题为《Long Non-Coding RNA Expression Profiles in Hereditary Haemorrhagic Telangiectasia》。配套论文《Long Non-Coding RNA Expression Profiles in Hereditary Haemorrhagic Telangiectasia》发表于 PLoS ONE（2014），DOI：10.1371/journal.pone.0090272。源站首次发布：2014-03-06。

【数据内容】

源站原始描述：Hereditary Haemorrhagic Telangiectasia (HHT) is an autosomal dominantly inherited vascular disease characterized by the presence of mucocutaneous telangiectasia and arteriovenous malformations in visceral organs. HHT is predominantly caused by mutations in ENG and ACVRL1, which both belong to the TGF-β signalling pathway. The exact mechanism of how haploinsufficiency of ENG and ACVRL1 leads to HHT manifestations remains to be identified. As long non-coding RNAs (lncRNAs) are increasingly recogni…

【数据结构与技术规格】

文件数 11 个，合计 7.74 MB。Figure_S1.tif：image/tiff，673.10 KB。Figure_S2.tif：image/tiff，827.78 KB。Figure_S3.tif：image/tiff，833.14 KB。数据集 DOI：10.1371/journal.pone.0090272。

【主题与分类】

源站学科分类：Biological Sciences、Medicine。主题标签：Biochemistry、Nucleic acids、rna、biophysics、Computational biology、genomics、Genome analysis tools、Gene ontologies、Molecular genetics、Gene regulation。

【适用方向】

源站学科分类标注为 Biological Sciences、Medicine。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Long_Non_Coding_RNA_Expression_Profiles_in_Hereditary_Haemorrhagic_Telangiectasia_/954014

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：M. Tørring, Pernille; Jakob Larsen, Martin; D. Kjeldsen, Anette; Bomme Ousager, Lilian; Tan, Qihua; Brusgaard, Klaus (2016). Long Non-Coding RNA Expression Profiles in Hereditary Haemorrhagic Telangiectasia. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-08，引用时请注意版本时效。