按INTERMACS分级的模型结果

包含LVAD成本效果分析模型结果,按INTERMACS心衰分级分层。

Figshare
2024-12-04 更新
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表格existing economic evaluationsdisease severity modifiers748 per qaly46 &# 8211uk healthcare perspectiveoptimal medical therapyongoing outpatient costsheart failure severityci &# 163&# 163ongoing costsheart failure
Model outcomes by INTERMACS profiles.

基本信息

模态
表格
大小
0.000005632 GB
许可
CC BY 4.0
创建/更新时间
2024-12-04
版本
v1

资源简介

按INTERMACS分级的模型结果

【数据集背景】

本数据集源站标题为《Model outcomes by INTERMACS profiles.》。源站首次发布:2024-12-04。

【数据内容】

源站原始描述:Objectives Left Ventricular Assist Devices (LVADs) for destination therapy (DT) are used in many countries but in some, like the UK, LVADs are not commissioned due to uncertainty around their cost-effectiveness. Existing economic evaluations of LVADs for these patients have limitations. This study aimed to estimate the cost-effectiveness of LVADs as destination therapy, compared to optimal medical therapy, in the UK. Methods A cost-utility analysis from a UK healthcare perspective was conducted,…

【数据结构与技术规格】

文件数 1 个,合计 5.63 KB。Table 6.xls:application/vnd.ms-excel,5.63 KB。数据集 DOI:10.1371/journal.pone.0312912.t006。

【主题与分类】

源站学科分类:Medicine、Biotechnology、Science Policy。主题标签:existing economic evaluations、disease severity modifiers、748 per qaly、46 &# 8211、uk healthcare perspective、optimal medical therapy、ongoing outpatient costs、heart failure severity、ci &# 163、&# 163。

【适用方向】

结构化表格数据可直接用于统计建模、特征工程与队列分析。

【获取与许可】

源站页面:https://plos.figshare.com/articles/dataset/Model_outcomes_by_INTERMACS_profiles_/27962868

使用许可:CC BY 4.0(https://creativecommons.org/licenses/by/4.0/)。

规范引用:Avşar, Tuba Saygın; Jackson, Louise; Barton, Pelham; Beese, Sophie; Lim, Hoong S.; Quinn, David; et al. (2024). Model outcomes by INTERMACS profiles.. PLOS ONE. Dataset

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下载信息

注册下载

需要注册 Kaggle 账号并登录后下载,适合需要跟踪下载记录和使用 API 的用户。

暂未开放

公开下载

无需注册即可直接获取公开样本或文档,适合快速预览和评估数据集质量。

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公开数据集受托下载与技术交付服务。

提供高速下载与技术交付服务(收技术服务费,非数据销售)

暂未开放

当前数据集主要来源为 Kaggle 公开托管,完整影像包建议通过原始链接或 Kaggle API 获取。

使用方式

数据集获取(Figshare)

命令行下载

curl -L -o "Table 6.xls" "https://ndownloader.figshare.com/files/50978283"

文件清单

  • Table 6.xls(5.63 KB)

文件总体积 5.63 KB(源站 API 实测)。

数据加载示例(图像类)

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

Objectives
Left Ventricular Assist Devices (LVADs) for destination therapy (DT) are used in many countries but in some, like the UK, LVADs are not commissioned due to uncertainty around their cost-effectiveness. Existing economic evaluations of LVADs for these patients have limitations. This study aimed to estimate the cost-effectiveness of LVADs as destination therapy, compared to optimal medical therapy, in the UK.
Methods
A cost-utility analysis from a UK healthcare perspective was conducted, using a Markov model. The model incorporated the impact of major events and complications. Sub-group analyses considered different severities of heart failure on cost-effectiveness. Uncertainty was measured in deterministic and probabilistic sensitivity analyses.
Results
LVAD produced additional 2.78 (95% CI 2.46–3.14) QALYs at an incremental cost of £152,329 (95% CI £125,665 - £181,812) compared to medical management, giving an incremental cost-effectiveness ratio (ICER) of £54,748 per QALY. The ICER remained above the accepted thresholds of cost-effectiveness in the UK if a small proportion of patients receiving LVAD becomes eligible for a heart transplant and for all subgroups based on heart failure severity. The deterministic sensitivity analysis showed that the ongoing outpatient costs had a significant impact on the results.
Conclusions
Our analysis found that LVADs are not cost-effective as destination therapy in the UK if a willingness to pay threshold of £50,000 per QALY gained or disease severity modifiers, were applied. Robust data on ongoing costs for LVAD and medical management are needed.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.1371/journal.pone.0312912.t006(source: https://plos.figshare.com/articles/dataset/Model_outcomes_by_INTERMACS_profiles_/27962868)。

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