荷兰高心血管风险的高胆固醇血症或混合型血脂异常患者的治疗与低密度脂蛋白胆固醇水平:一项基于人群的横断面研究

基于PHARMO数据库的荷兰横断面研究,分析高心血管风险的高胆固醇血症或混合型血脂异常患者的治疗模式、LDL-C水平和医疗资源利用。

Kuiper, Josephina; Bilitou, Aikaterini; Herings, Ron M. C.; Jukema, J. Wouter; Anastassopoulou, Anastassia; Beest, Fernie J. A. Penning-van; Postma, Maarten J.; Heintjes, Edith M.Kuiper, Josephina; Bilitou, Aikaterini; Herings, Ron M. C.; Jukema, J. Wouter; Anastassopoulou, Anastassia; Beest, Fernie J. A. Penning-van; Postma, Maarten J.; Heintjes, Edith M.
Taylor & Francis Group
2022-12-30 更新
浏览 13
表格Hypercholesterolaemiamixed dyslipidaemiahigh cardiovascular riskatherosclerotic cardiovascular diseaseantihyperlipidaemicslow-density lipoprotein cholesterol
Treatment and low-density lipoprotein cholesterol levels in patients with hypercholesterolaemia or mixed dyslipidaemia at high or very high cardiovascular risk: a population-based cross-sectional study in the Netherlands

基本信息

模态
表格
大小
0.00021934 GB
许可
CC BY 4.0
创建/更新时间
2022-12-30
版本
v2

资源简介

荷兰高心血管风险的高胆固醇血症或混合型血脂异常患者的治疗与低密度脂蛋白胆固醇水平:一项基于人群的横断面研究

【一句话概览】

本数据集是 figshare 公开的结构化表格数据集,收录 2 个文件、合计 219.34 KB,主题涵盖 Hypercholesterolaemia、mixed dyslipidaemia、high cardiovascular risk、atherosclerotic cardiovascular disease、antihyperlipidaemics,可用于统计建模、特征工程与队列分析,CC BY 4.0 许可开放获取。

【数据集背景】

本数据集源站标题为《Treatment and low-density lipoprotein cholesterol levels in patients with hypercholesterolaemia or mixed dyslipidaemia at high or very high cardiovascular risk: a population-based cross-sectional study in the Netherlands》。配套论文《Treatment and low-density lipoprotein cholesterol levels in patients with hypercholesterolaemia or mixed dyslipidaemia at high or very high cardiovascular risk: a population-based cross-sectional study in the Netherlands》发表于 Current Medical Research and Opinion(2022),DOI:10.1080/03007995.2022.2129228。源站首次发布:2022-10-14。

【数据内容】

源站原始描述:To describe treatment patterns, low-density lipoprotein cholesterol (LDL-C) levels and healthcare resource utilization (HCRU) in the Netherlands in 2018 of patients with hypercholesterolaemia or mixed dyslipidaemia at high or very high cardiovascular (CV) risk. From the PHARMO Database Network adult patients with a diagnosis or receiving lipid lowering therapy (LLT) between 2009 and 2018 were selected. Patients at high or very high CV risk according to 2016 ESC/EAS guidelines with recorded LDL-C…

中文译文(机器翻译,仅供快速理解,请以原文为准):描述2018年荷兰高或极高心血管(CV)风险的高胆固醇血症或混合型血脂异常患者的治疗模式、低密度脂蛋白胆固醇(LDL-C)水平及医疗资源利用(HCRU)情况。 从PHARMO数据库网络中选取2009年至2018年间确诊或接受降脂治疗(LLT)的成年患者。纳入根据2016年ESC/EAS指南判定为高或极高CV风险、有LDL-C水平记录、且在2018年接受LLT治疗或被判定为他汀不耐受的患者。评估LLT治疗模式、LDL-C水平及HCRU(全科医生[GP]就诊和住院情况)。 研究人群包括54,346例患者,其中70%为极高CV风险,30%为高CV风险。大多数(93%)接受他汀单药治疗,多为中等强度(73%)或高强度(15%)。仅3%接受他汀联合依折麦布治疗。根据治疗算法估算,他汀不耐受率为3%。平均LDL-C随LLT强度增加而降低。总体而言,74%达到LDL-C 2018年荷兰高或极高CV风险患者的高胆固醇血症和混合型血脂异常治疗欠佳。为进一步降低CV风险,需要采用附加治疗的替代治疗策略。

【数据结构与技术规格】

文件数 2 个,合计 219.34 KB。icmo_a_2129228_sm1197.docx:application/vnd.openxmlformats-officedocument.wordprocessingml.document,25.25 KB。icmo_a_2129228_sm1196.docx:application/vnd.openxmlformats-officedocument.wordprocessingml.document,194.09 KB。数据集 DOI:10.6084/m9.figshare.21220361.v2。

【主题与分类】

源站学科分类:Medicine、Ecology、Biological Sciences not elsewhere classified、Cancer、Science Policy、Infectious Diseases。主题标签:Hypercholesterolaemia、mixed dyslipidaemia、high cardiovascular risk、atherosclerotic cardiovascular disease、antihyperlipidaemics、low-density lipoprotein cholesterol。

【适用方向】

结构化表格数据可直接用于统计建模、特征工程与队列分析。

【获取与许可】

源站页面:https://tandf.figshare.com/articles/dataset/Treatment_and_low-density_lipoprotein_cholesterol_levels_in_patients_with_hypercholesterolaemia_or_mixed_dyslipidaemia_at_high_or_very_high_cardiovascular_risk_a_population-based_cross-sectional_study_in_the_Netherlands/21220361

使用许可:CC BY 4.0(https://creativecommons.org/licenses/by/4.0/)。

规范引用:Treatment and low-density lipoprotein cholesterol levels in patients with hypercholesterolaemia or mixed dyslipidaemia at high or very high cardiovascular risk: a population-based cross-sectional study in the Netherlands. Taylor & Francis. Heintjes, Edith M.; Anastassopoulou, Anastassia; Kuiper, Jos…

【使用注意】

· 源站最后修改于 2023-06-01,引用时请注意版本时效。

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下载信息

注册下载

需要注册 Kaggle 账号并登录后下载,适合需要跟踪下载记录和使用 API 的用户。

暂未开放

公开下载

无需注册即可直接获取公开样本或文档,适合快速预览和评估数据集质量。

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有偿下载

公开数据集受托下载与技术交付服务。

提供高速下载与技术交付服务(收技术服务费,非数据销售)

暂未开放

当前数据集主要来源为 Kaggle 公开托管,完整影像包建议通过原始链接或 Kaggle API 获取。

使用方式

数据集获取(Figshare)

命令行下载

curl -L -o "icmo_a_2129228_sm1197.docx" "https://ndownloader.figshare.com/files/37631507"
curl -L -o "icmo_a_2129228_sm1196.docx" "https://ndownloader.figshare.com/files/37631510"

文件清单

  • icmo_a_2129228_sm1197.docx(25.25 KB)
  • icmo_a_2129228_sm1196.docx(194.09 KB)

文件总体积 219.34 KB(源站 API 实测)。

数据加载示例(图像类)

from PIL import Image
import glob, os

files = (glob.glob(os.path.join(path, "**", "*.png"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.jpg"), recursive=True)
       + glob.glob(os.path.join(path, "**", "*.tif"), recursive=True))
print("图像文件数:", len(files))
img = Image.open(files[0]); print("尺寸/模式:", img.size, img.mode)

# torchvision Dataset 方式:
# from torchvision import datasets
# ds = datasets.ImageFolder(path)  # 要求 子目录=类别

目录组织与标注格式以源站说明和下载后实际文件为准。

数据说明

To describe treatment patterns, low-density lipoprotein cholesterol (LDL-C) levels and healthcare resource utilization (HCRU) in the Netherlands in 2018 of patients with hypercholesterolaemia or mixed dyslipidaemia at high or very high cardiovascular (CV) risk.
From the PHARMO Database Network adult patients with a diagnosis or receiving lipid lowering therapy (LLT) between 2009 and 2018 were selected. Patients at high or very high CV risk according to 2016 ESC/EAS guidelines with recorded LDL-C levels who were treated with LLT or were characterized as statin intolerant in 2018 were included. LLT treatment patterns, LDL-C levels and HCRU (General Practitioner [GP] consultations and hospitalizations) were assessed.
The study population included 54,346 patients, of which 70% were at very high CV risk and 30% at high CV risk. The majority (93%) received statin monotherapy, mostly of moderate (73%) or high (15%) intensity. Only 3% received a combination of statin and ezetimibe. Statin intolerance, based on a treatment algorithm, was estimated at 3%. Average LDL-C decreased with LLT intensity. Overall, 74% reached LDL-C The treatment of hypercholesterolaemia and mixed dyslipidaemia in patients at high or very high CV risk in the Netherlands was suboptimal in 2018. To further lower CV risk alternative treatment strategies using add-on therapies are needed.

许可

CC BY 4.0

引用

学术使用请引用 DOI 10.6084/m9.figshare.21220361.v2(source: https://tandf.figshare.com/articles/dataset/Treatment_and_low-density_lipoprotein_cholesterol_levels_in_patients_with_hypercholesterolaemia_or_mixed_dyslipidaemia_at_high_or_very_high_cardiovascular_risk_a_population-based_cross-sectional_study_in_the_Netherlands/21220361)。

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