一种源自人类去势抵抗性前列腺癌的成骨/溶骨性病变新小鼠模型

资源简介

一种源自人类去势抵抗性前列腺癌的成骨/溶骨性病变新小鼠模型

【数据集背景】

本数据集源站标题为《A New Murine Model of Osteoblastic/Osteolytic Lesions from Human Androgen-Resistant Prostate Cancer》。配套论文《A New Murine Model of Osteoblastic/Osteolytic Lesions from Human Androgen-Resistant Prostate Cancer》发表于 PLoS ONE（2013），DOI：10.1371/journal.pone.0075092。源站首次发布：2013-09-19。

【数据内容】

源站原始描述：Background Up to 80% of patients dying from prostate carcinoma have developed bone metastases that are incurable. Castration is commonly used to treat prostate cancer. Although the disease initially responds to androgen blockade strategies, it often becomes castration-resistant (CRPC for Castration Resistant Prostate Cancer). Most of the murine models of mixed lesions derived from prostate cancer cells are androgen sensitive. Thus, we established a new model of CRPC (androgen receptor (AR) negat…

【数据结构与技术规格】

文件数 6 个，合计 6.93 MB。Figure_S1.tif：image/tiff，641.90 KB。Figure_S2.tif：image/tiff，3.54 MB。Figure_S3.tif：image/tiff，1.92 MB。数据集 DOI：10.1371/journal.pone.0075092。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：murine、lesions、androgen-resistant、prostate。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_A_New_Murine_Model_of_Osteoblastic_Osteolytic_Lesions_from_Human_Androgen_Resistant_Prostate_Cancer_/804084

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Fradet, Anaïs; Sorel, Hélène; Depalle, Baptiste; Marie Serre, Claire; Farlay, Delphine; Turtoi, Andrei; et al. (2016). A New Murine Model of Osteoblastic/Osteolytic Lesions from Human Androgen-Resistant Prostate Cancer. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-02，引用时请注意版本时效。