Claudin-4缺陷导致尿路上皮增生和致死性肾积水

资源简介

Claudin-4缺陷导致尿路上皮增生和致死性肾积水

【数据集背景】

本数据集源站标题为《Claudin-4 Deficiency Results in Urothelial Hyperplasia and Lethal Hydronephrosis》。配套论文《Claudin-4 Deficiency Results in Urothelial Hyperplasia and Lethal Hydronephrosis》发表于 PLoS ONE（2012），DOI：10.1371/journal.pone.0052272。源站首次发布：2012-12-21。

【数据内容】

源站原始描述：Claudin (Cld)-4 is one of the dominant Clds expressed in the kidney and urinary tract, including selective segments of renal nephrons and the entire urothelium from the pelvis to the bladder. We generated Cldn4−/− mice and found that these mice had increased mortality due to hydronephrosis of relatively late onset. While the renal nephrons of Cldn4−/− mice showed a concomitant diminution of Cld8 expression at tight junction (TJ), accumulation of Cld3 at TJ was markedly enhanced in compensation a…

【数据结构与技术规格】

文件数 4 个，合计 6.61 MB。Figure_S1.tif：image/tiff，195.74 KB。Figure_S2.tif：image/tiff，3.03 MB。Figure_S3.tif：image/tiff，2.41 MB。数据集 DOI：10.1371/journal.pone.0052272。

【主题与分类】

源站学科分类：Physiology、Cancer、Cell Biology、Marine Biology。主题标签：claudin-4、deficiency、results、urothelial、hyperplasia、lethal、hydronephrosis。

【适用方向】

源站学科分类标注为 Physiology、Cancer、Cell Biology、Marine Biology。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Claudin_4_Deficiency_Results_in_Urothelial_Hyperplasia_and_Lethal_Hydronephrosis__/115301

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Fujita, Harumi; Hamazaki, Yoko; Noda, Yumi; Oshima, Masanobu; Minato, Nagahiro (2016). Claudin-4 Deficiency Results in Urothelial Hyperplasia and Lethal Hydronephrosis. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-01，引用时请注意版本时效。