黑色素瘤基因网络重连研究：探索黑色素瘤进展阶段及驱动要素

资源简介

黑色素瘤基因网络重连研究：探索黑色素瘤进展阶段及驱动要素

【数据集背景】

本数据集源站标题为《Gene Network Rewiring to Study Melanoma Stage Progression and Elements Essential for Driving Melanoma》。配套论文《Gene Network Rewiring to Study Melanoma Stage Progression and Elements Essential for Driving Melanoma》发表于 PLOS ONE（2015），DOI：10.1371/journal.pone.0142443。源站首次发布：2015-11-11。

【数据内容】

源站原始描述：Metastatic melanoma patients have a poor prognosis, mainly attributable to the underlying heterogeneity in melanoma driver genes and altered gene expression profiles. These characteristics of melanoma also make the development of drugs and identification of novel drug targets for metastatic melanoma a daunting task. Systems biology offers an alternative approach to re-explore the genes or gene sets that display dysregulated behaviour without being differentially expressed. In this study, we have…

【数据结构与技术规格】

文件数 11 个，合计 6.66 MB。S1_Fig.tif：image/tiff，968.23 KB。S2_Fig.tif：image/tiff，755.92 KB。S3_Fig.tif：image/tiff，716.54 KB。数据集 DOI：10.1371/journal.pone.0142443。

【主题与分类】

源站学科分类：Uncategorised。主题标签：disease gene sets、melanoma driver genes、melanoma progression、disease genes、metastatic melanoma、gene expression profiles、novel drug targets、rewiring network connections、systems Biology Studies、shortlisted disease genes。

【适用方向】

源站学科分类标注为 Uncategorised。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Gene_Network_Rewiring_to_Study_Melanoma_Stage_Progression_and_Elements_Essential_for_Driving_Melanoma_/1600689

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Kaushik, Abhinav; Bhatia, Yashuma; Ali, Shakir; Gupta, Dinesh (2016). Gene Network Rewiring to Study Melanoma Stage Progression and Elements Essential for Driving Melanoma. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。