疾病严重程度与死亡率在实验性移植物抗宿主病小鼠模型中可独立调控

资源简介

疾病严重程度与死亡率在实验性移植物抗宿主病小鼠模型中可独立调控

【数据集背景】

本数据集源站标题为《Disease Severity and Mortality Can Be Independently Regulated in a Mouse Model of Experimental Graft versus Host Disease》。配套论文《Disease Severity and Mortality Can Be Independently Regulated in a Mouse Model of Experimental Graft versus Host Disease》发表于 PLOS ONE（2015），DOI：10.1371/journal.pone.0118079。源站首次发布：2015-02-02。

【数据内容】

源站原始描述：Graft versus host disease (GVHD) is the major limitation of allogeneic hematopoietic stem cell transplantation (HSCT) presenting high mortality and morbidity rates. However, the exact cause of death is not completely understood and does not correlate with specific clinical and histological parameters of disease. Here we show, by using a semi-allogeneic mouse model of GVHD, that mortality and morbidity can be experimentally separated. We injected bone marrow-derived dendritic cells (BMDC) from NO…

【数据结构与技术规格】

文件数 2 个，合计 755.53 KB。S1_Fig.pdf：application/pdf，724.59 KB。S2_Fig.pdf：application/pdf，30.94 KB。数据集 DOI：10.1371/journal.pone.0118079。

【主题与分类】

源站学科分类：Biological Sciences。主题标签：20 days、Host Disease Graft、allogeneic hematopoietic、histological parameters、epithelial integrity maintenance、score、hsct、Cell transplantation、host disease、mortality。

【适用方向】

源站学科分类标注为 Biological Sciences。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/_Disease_Severity_and_Mortality_Can_Be_Independently_Regulated_in_a_Mouse_Model_of_Experimental_Graft_versus_Host_Disease_/1299823

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：G. Galvani, Rômulo; Lemos, Ramon; B. Areal, Rômulo; A. Salvador, Pollyanna; S. Zamboni, Dario; Luiz M. Wanderley, João; et al. (2016). Disease Severity and Mortality Can Be Independently Regulated in a Mouse Model of Experimental Graft versus Host Disease. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-05-31，引用时请注意版本时效。