Nav1.7调控：一种在背根神经节中表达的保守SCN9A天然反义转录本

资源简介

Nav1.7调控：一种在背根神经节中表达的保守SCN9A天然反义转录本

【数据集背景】

本数据集源站标题为《Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia》。配套论文《Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia》发表于 PLOS ONE（2015），DOI：10.1371/journal.pone.0128830。源站首次发布：2015-06-02。

【数据内容】

源站原始描述：The Nav1.7 voltage-gated sodium channel, encoded by SCN9A, is critical for human pain perception yet the transcriptional and post-transcriptional mechanisms that regulate this gene are still incompletely understood. Here, we describe a novel natural antisense transcript (NAT) for SCN9A that is conserved in humans and mice. The NAT has a similar tissue expression pattern to the sense gene and is alternatively spliced within dorsal root ganglia. The human and mouse NATs exist in cis with the sense…

【数据结构与技术规格】

文件数 6 个，合计 415.86 KB。S1_Fig.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，44.10 KB。S2_Fig.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，26.32 KB。S3_Fig.docx：application/vnd.openxmlformats-officedocument.wordprocessingml.document，166.05 KB。数据集 DOI：10.1371/journal.pone.0128830。

【主题与分类】

源站学科分类：Uncategorised。主题标签：5y、dorsal root ganglia、293a、SCN 9A、Tissue Expression Pattern、sense gene、hek、downregulate Nav 1.7 mRNA、Conserved SCN 9A Natural Antisense Transcript、SCN 9A locus。

【适用方向】

源站学科分类标注为 Uncategorised。

【获取与许可】

源站页面：https://plos.figshare.com/articles/dataset/Regulation_of_Na_v_1_7_A_Conserved_SCN9A_Natural_Antisense_Transcript_Expressed_in_Dorsal_Root_Ganglia/1434084

使用许可：CC BY 4.0（https://creativecommons.org/licenses/by/4.0/）。

规范引用：Koenig, Jennifer; Werdehausen, Robert; E. Linley, John; M. Habib, Abdella; Vernon, Jeffrey; Lolignier, Stephane; et al. (2016). Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia. PLOS ONE. Dataset

【使用注意】

· 源站最后修改于 2023-06-04，引用时请注意版本时效。